Correction to Evolution of a Novel, Orally Bioavailable Series of PI3KÎ´

Evolution of a Novel, Orally Bioavailable Series of ... - ACS Publications

Jul 18, 2016 - Evolution of a Novel, Orally Bioavailable Series of PI3KÎ´ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease. Augustin ...

Evolution of a Novel, Orally Bioavailable Series of PI3KÎ´ Inhibitors

Jul 18, 2016 - Evolution of a Novel, Orally Bioavailable Series of PI3KÎ´ Inhibitors from an Inhaled Lead for the Treatment of Respiratory Disease.


... Chemistry, University of Strathclyde, 295 Cathedral Street, Glasgow G1 1XL, U.K.. J. Med. Chem. , 2016, 59 (15), pp 7239â7251. DOI: 10.1021/acs.jmedchem.6b00799. Publication Date (Web): July 18, 2016. Copyright Â© 2016 American Chemical Society


Jul 18, 2016 - A four-step process of high-quality modeling of existing data, deconstruction, identification of replacement cores, and an innovative synthetic regrowth strategy led to the rapid discovery of a novel oral series of PI3KÎ´ inhibitors wi

Correction to Evolution of a Novel, Orally Bioavailable Series of PI3KÎ´

Aug 22, 2016 - Christopher N. Luscombe, Josie Morrell, Simon Peace,* David Perez, Paul Rowland, Christopher J. Tame,. Sorif Uddin, Giovanni Vitulli, and ...

Evolution of a Novel, Orally Bioavailable Series of ... - ACS Publications

Jul 18, 2016 - from an Inhaled Lead for the Treatment of Respiratory Disease. Augustin ... diseases, including respiratory inflammation.1,2 They comprise.

Correction to Evolution of a Novel, Orally Bioavailable Series of PI3KÎ´

Aug 22, 2016 - File failed to load: https://cdn.mathjax.org/mathjax/contrib/a11y/accessibility-menu.js. ADVERTISEMENT · Log In Register · Cart · ACS · ACS Publications · C&EN · CAS · ACS Publications. ACS Journals. ACS eBooks; C&EN Global Enterprise.

Discovery of a Novel Series of Potent and Orally Bioavailable

May 1, 2012 - Our high-throughput screening (HTS) campaign revealed two hits that were nominated for further optimization studies. The in vitro activity of the ...


May 1, 2012 - Department of Drug Discovery, Exelixis, 169 Harbor Way, South San Francisco, California 94083, United States. J. Med. Chem. , 2012, 55 (11), pp 5467â5482 ... Citation data is made available by participants in Crossref's Cited-by Linki


May 1, 2012 - Matthew Williams, John M. Nuss, Eric Brooks, Paul Foster, Leanne Goon, Nathan Heald, Charles Holst,. Christopher ... Thomas Stout, Xiang Wu, Michael F. Yakes, Peiwen Yu, Wentao Zhang, Peter Lamb, and Olivia Raeber.

Correction to Evolution of a Novel, Orally Bioavailable Series of PI3KÎ´

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