Correction to Ochratoxin A-Induced Apoptosis of IPEC-J2 Cells

Correction to Ochratoxin A‑Induced Apoptosis of IPEC-J2 Cells through ROS-Mediated Mitochondrial Permeability Transition Pore. Opening Pathway...
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Addition/Correction Cite This: J. Agric. Food Chem. XXXX, XXX, XXX−XXX

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Correction to Ochratoxin A‑Induced Apoptosis of IPEC-J2 Cells through ROS-Mediated Mitochondrial Permeability Transition Pore Opening Pathway Hong Wang, Ying Chen, Nianhui Zhai, Xingxiang Chen, Fang Gan, Hu Li, and Kehe Huang* J. Agric. Food Chem. 2017, 65 (48), 10630−10637. DOI: 10.1021/acs.jafc.7b04434

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Page 10632. Figure 3c as originally published was incorrect. The correct Figure 3 is given below.

Figure 3. OTA-induced ROS production and mPTP opening in IPEC-J2 cells. IPEC-J2 cells were exposed with OTA (2, 4, and 8 μM) for 12 h and then stained with H2DCFDA (for measurement of intracellular ROS), MitoSOX Red (for measurement of mitochondria ROS), or calcein-AM (for measurement of mPTP opening). (a and b) Shown are representative confocal images for DCF staining. (c) Cells were stained with H2DCFDA and MitoTracker Red (red, localized to mitochondria). Overlay images (yellow) indicated that mitochondria are the major source of intracellular ROS induced by OTA. (d and e) Shown are representative confocal images for MitoSOX Red staining. (f and g) Shown are representative confocal images for calcein staining. The average fluorescence intensity was expressed as the percentage compared to the control group (set as 100%). Among the groups (a, d, and f), (A) control, (B) 2 μM OTA, (C) 4 μM OTA, and (D) 8 μM OTA. Data in panels b, e, and g represent the mean ± SEM of three separate experiments (n = 6). (∗) p < 0.05 and (∗∗) p < 0.01 compared to the control.

© XXXX American Chemical Society

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DOI: 10.1021/acs.jafc.8b04009 J. Agric. Food Chem. XXXX, XXX, XXX−XXX