I N D U S T R I A L A N D E N G I N E E R I N G CHEMISTRY
2610
studied were found to be pronounced. Conditions for the partial hydrolysis and fractionation of any particular dextran to obtain a depolymerized fraction suitable for preparing injection solutions must be established individually. Reaction rate constants were derived for hydrolysis of the dextrans. Comparison was made between the hydrolysis conditions used and those theoretically required from statistical considerations. ACKNOWLEDG-WENT
This research program on dextran has been carried out with the cooperation of a number of workers a t the Northern Utilization Research Branch. The authors wish particularly to thank V. E. Sohns and H. F. Conway for assistance in the pilot plant operations; J. C. Rankin for periodate analyses; G. E. Lauterbach for assistance in the separation of the component fractions of the K R R L B-742 dextran; C. S. \Vise for fructose analyses; Phyllis L. Patrick, C. A. Glass, and G. Gill for some of the analyses for reducing power and viscosity; C. H. VanEtten and H. F. %bel for ash, nitrogen, and heavy metals determinations; H. Davis for assistance in the hydrolysis studies; H. h l Tsuchiya, Allene Jeanes, and C. A. Wilham for supplying the high molecular weight dextrans used as raw materials for laboratory study; R. J. Dimler and F. R. Senti for helpful discussions of various phases of this work; and R. T. Milner for his keen interest which provided stimulation for these studies. LITERATURE CITED
(1) Hellman, K. N., National Research Council, Subcommittee on
Shock, and Northern Regional Research Laboratory, Peoria, Ill., “Report of Working Conference on Dextran,” p. 36, Oct. 29,1951.
Vol. 46, No. 12
Ishell, H. S.. Snyder, C. F., and associates, J . Research Natt. BUT.Standards, 50,81-6 (1953). Jeanes, A . , Haynes, W. C., and associates, J . Am. Chem. Soc., 76, in press. Jeanes, A , , Schieltz, ?;. C., and Wilham, C. A., J . B i d . Chem,., 176, 617--27 (1948). Jeanes, A , and Wilham, C. A., J. Am. Chem. SOC.,72, 2655-7 (1950). Jeanes, A., Wilham, C. A , and M i e n , J. C., J . Biol. Chem., 176, 603-15 (1948). Ber., 63, 1503-9 (1930). Kuhn, W., Lohmar, R., J . Am. Chent. SOC:,74, 4974 (1952). Montroll. E. W., and Simha, R., J . Chern. Phys., 8, 721-7 (1940). Seensk K e m . Tidskr., 54, 50-60 Alyrback, K., and Thorsell, W., (1942). Seifter, S., Dayton, S.,and associates, A r c h . Biochem., 25, 191200 (1950,.
Sillh, L. G., Siwnsk Kern. Tidskr., 55,266-79 (1943). Swanson, 11. A , , and Cori, C. F., .l.Biol. Chem., 172,797 (1948). U. S.Military Medical Purchase Description No. 4 , Sept. 19, 1952 (Stock No. 1-161-890, Dextran Injection, R I - l 6%, 500 cc., Armed Services Medical Procurement Agency, Brooklyn 1, N . Y . ) . Wise. C. S., Dimler, R. J . , and associates, presented before the Division of Carbohydrate Chemistry, 124th Meeting, B C S , Chicago, Ill., 1953. Wolff, I. A, Xehltretter, C. L., and associates, IND. Exc,. CHEM.,46,370-7 (1954). Wolfrom, AI. L., Lassettre, E. N., and O’Neill, A. N., J . Am. Chem. Soc., 73, 595-9 (1951); Jones, R. W., Dimler, R. J., and Rist, C. E., presented before the Division of Carbohydrate Chemistry, 124th Meeting, ACS, Chicago. Ill., 1953. RECEIVEDfor review April 19, 1954. ACCEPTEDJ u l y 24, 1954, Presented before the Division of Carbohydrate Chemistry a t t h e 126th Meeting of the AMERICAN CHEMICAL SOCIETY,Kansas City, 310.
Theory of Extrusisn-Corrections I n the Symposium on Theory of Extrusion [IKD. ENG.CHEnf., 45, 970-93 (1953)j several errors occurred. The corrections printed here give the page number a t the left, followed in parentheses by the page number of the reprint booklet of the symposium. 970 (970) Equation 1 and the line preceding it, read dv/dy for
Wdv. 971 (971) second column, line 12, read read v / V for s / V .
7
for S.
I n Figure 2
972 (972) Equation 2, minus sign should be plus sign. tion 3 should read: QP
=
n h h3 cos
FP
(a
r2D2h tan ?I=-
2
(a
985 (981), bracket in numerator of Equation 7 should read:
Equa-
dz dz
980 (990), Equation 15 should read:
Equation 6 should read: QD
=
n r D N b 2 cos3 9 F D
987 (983), in Equations 2, 3, and 4 read 988 (984), Equation 17 should read:
T
for S.
973 (973), (E), date should be 1842.
977 (977) Equation 24 should read:
A h sin (a cos p 1 ~ h z s i n 2(a
-+
Q =
Equation 26 should read: sin2
(a
=
1 rDh3
m L + 2 979 (989), symbols w and 7 are not defined and definitions are not expliclt in ( 4 ) . They are defined by w =
($ +
r2D2L
In Equations 7 through 20: If the land width is not negligible-that is, if b l l is appreciably less than 1.00-dA, dZ1, and Z1 as given dl be high by the factor tlh. The diameter D in dZ1 and 2, is the mean diameter, defined in the first paper. The diameter in dZa and Z Z should be the major diameter. Major diameter equals mean diameter plus thread depth.
(985)) ( 2 ) read 982 for 978. 990 (986), Equation 25 read dv/dy for ds/dy.
(988), ( 2 ) read 970 for 983.
(5),read 983 for 987.
