Cyclin A as ... - ACS Publications

25 Jun 2005 - Pevarello, Brasca, Orsini, Traquandi, Longo, Nesi, Orzi, Piutti, Sansonna, Varasi, Cameron, Vulpetti, Roletto, Alzani, Ciomei, Albanese,...
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5058

J. Med. Chem. 2005, 48, 5058

Additions and Corrections

2005, Volume 45

Paolo Pevarello,* Maria Gabriella Brasca, Paolo Orsini, Gabriella Traquandi, Antonio Longo, Marcella Nesi, Fabrizio Orzi, Claudia Piutti, Pietro Sansonna, Mario Varasi, Alexander Cameron, Anna Vulpetti, Fulvia Roletto, Rachele Alzani, Marina Ciomei, Clara Albanese, Wilma Pastori, Aurelio Marsiglio, Enrico Pesenti, Francesco Fiorentini, Jim R. Bischoff, Ciro Mercurio: 3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 2. Lead Optimization. Page 2945. Compounds 43, 44, and 15a in Scheme 4 were drawn incorrectly. The correct structures are the regioisomers shown below (and in accordance with the structure of the final derivative 15 on page 2947).

Page 2952. The names of compounds 43 and 15a in the Experimental Section are incorrect. The correct names are the following: 43, 1-[4-(1-methoxycarbonylethyl)phenyl]-2-oxopyrrolidine-3-carboxylic acid; 15a, 2-[4-(3-carbamoyl-2-oxopyrrolidin-1-yl)phenyl]propionic acid. JM0580252 10.1021/jm0580252 Published on Web 06/25/2005

10.1021/jm0580252 CCC: $30.25 © 2005 American Chemical Society Published on Web 06/25/2005