Monograph pubs.acs.org/doi/book/10.1021/acsreagents
Cyclohexanone Part 4, Monographs for Reagent Chemicals: General Descriptions, Specifications, and Tests eISBN: 9780841230460 Tom Tyner Chair, ACS Committee on Analytical Reagents James Francis Secretary, ACS Committee on Analytical Reagents
ABSTRACT This monograph for Cyclohexanone provides, in addition to common physical constants, a general description including typical appearance, applications, change in state (approximate), aqueous solubility, density, and pKa. The monograph also details the following specifications and corresponding tests for verifying that a substance meets ACS Reagent Grade specifications including: Assay, Color (APHA), Residue after Evaporation, and Water.
C6H10O
Formula Wt 98.14
CAS No. 108-94-1
GENERAL DESCRIPTION Typical appearance . . . . . . . . Applications . . . . . . . . . . . . . Change in state (approximate) . Aqueous solubility . . . . . . . . . Density . . . . . . . . . . . . . . . . pKa . . . . . . . . . . . . . . . . . .
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clear, oily liquid organic solvent boiling point, 154–156 °C 5 g in 100 mL at 30 °C 0.95 –6.8
SPECIFICATIONS General Use Assay . . . . . . . . . . . . . . . . . . . . . . . . . . . ≥99.0% C6H10O Maximum Allowable Color (APHA) . . . . . . . . . . . . . . . . . . . . . . 10
© 2017 American Chemical Society
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DOI:10.1021/acsreagents.4111 ACS Reagent Chemicals, Part 4
ACS Reagent Chemicals
Monograph
pubs.acs.org/doi/book/10.1021/acsreagents
Residue after evaporation . . . . . . . . . . . . . . 0.05% Water (H2O) . . . . . . . . . . . . . . . . . . . . . . . 0.05%
Specific Use Headspace Analysis Assay by GC–HS [Part 2: Chromatography; Recommended Procedures; Extraction−Concentration; Procedure for Headspace Analysis Suitability]. . . . . . . . . . . 99.9%
TESTS Assay Analyze the sample by gas chromatography using the parameters cited in [Part 2: Chromatography; Recommended Procedures; Gas Chromatography]. The following specific conditions are also required. Column . . . . . . . . . . . . . . . . . . . . . . . . . . Type I, methyl silicone Measure the area under all peaks and calculate the cyclohexanone content in area percent. Correct for water content.
Color (APHA) [Part 2: Measurement of Physical Properties; Color (APHA); Procedure for Color (APHA)].
Residue after Evaporation [Part 2: Gravimetric Methods; Residue after Evaporation]. Evaporate 100 g (105 mL) to dryness in a tared, preconditioned dish on a hot plate (~100 °C), and dry the residue at 105 °C for 30 min.
Water [Part 2: Titrimetric Methods; Water by the Karl Fischer Method; Coulometric Procedure; Coulometric Procedure for Samples Using Karl Fischer Reagent, Method 2]. Use 30 mL (24 g) of the sample and a methanol-free system to prevent ketal formation with liberation of water.
© 2017 American Chemical Society
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DOI:10.1021/acsreagents.4111 ACS Reagent Chemicals, Part 4
