Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor

Aug 18, 2014 - Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor (BILB 1941) with Demonstrated Antiviral Activity in Patients Chronicall...
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Discovery of the First Thumb Pocket 1 NS5B Polymerase Inhibitor (BILB 1941) with Demonstrated Antiviral Activity in Patients Chronically Infected with Genotype 1 Hepatitis C Virus (HCV) Pierre L. Beaulieu,* Michael Bös, Michael G. Cordingley, Catherine Chabot, Gulrez Fazal, Michel Garneau, James R. Gillard, Eric Jolicoeur, Steven LaPlante, Ginette McKercher, Martin Poirier, Marc-André Poupart, Youla S. Tsantrizos, Jianmin Duan, and George Kukolj J. Med. Chem. 2012, 55 (17), 7650−7666. DOI: 10.1021/jm3006788 Page 7665. Reference 24(f), change the name MgGowan to McGowan.

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dx.doi.org/10.1021/jm501225c | J. Med. Chem. XXXX, XXX, XXX−XXX