10730
J. Phys. Chem. C 2010, 114, 10730–10738
Fabrication and Use of Electroless Plated Polymer Surface-Enhanced Raman Spectroscopy Substrates for Viral Gene Detection Niranjan A. Malvadkar,† Gokhan Demirel,† Mary Poss,‡ Ali Javed,§ Walter J. Dressick,| and Melik C. Demirel*,† Department of Engineering Science and Infectious Disease Center, PennsylVania State UniVersity, UniVersity Park, PennsylVania 16802, Genelink, Hawthorne, New York 10532, and NaVal Research Laboratory, Code 6910, 4555 OVerlook AVenue, S.W., Washington, DC 20375 ReceiVed: February 20, 2010; ReVised Manuscript ReceiVed: May 6, 2010
Surface-enhanced Raman spectroscopy (SERS) substrates are prepared by electroless Ag metallization and vapor phase Au deposition on nanostructured poly(chloro-p-xylylene) (nanoPPX) templates. These substrates exhibit quasi-periodic nanomorphology inherited from the underlying nanoPPX template, resulting in highly reproducible SERS signal (
