Laboratory Experiment pubs.acs.org/jchemeduc
Synthesis and Application of Ratiometric and “Turn-On” Fluorescent pH Sensors: An Advanced Organic Undergraduate Laboratory Johnathon T. Hutt and Zachary D. Aron* Department of Chemistry, Indiana University, Bloomington, Indiana 47401, United States S Supporting Information *
ABSTRACT: An upper-division organic chemistry laboratory experiment exploring fluorescent sensing over two laboratory periods and part of a third is described. Two functionally distinct pH-responsive sensors are prepared through a dehydrative three-component coupling reaction. During the abbreviated (
