05/11/2015
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Upcoming ACS Webinars www.acs.org/acswebinars
Thursday, November 12, 2015
“Chemistry of Addiction” Anthony Rappé, Professor of Chemistry, Colorado State University Darren Griffen, Professor of Genetics, University of Kent
Thursday, November 19, 2015
“Prodrugs in Drug Discovery” John Higgins, Senior Principal Scientist and Network Technology Lead, Merck Nicholas Meanwell, Executive Director, Discovery Chemistry, Bristol-Myers Squibb
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[email protected] “From Truth Serum to Anesthesia: The Discovery and Uses of Sodium Thiopental”
Michael Matson Reservoir Engineer, Kinder Morgan CO2
David Harwell Asst. Director of Industry Member Programs, ACS
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05/11/2015
From Truth Serum to Anesthesia: The Discovery and Uses of Sodium Thiopental
Michael Matson, Kinder Morgan
Remember, remember, the 5th of November, The gunpowder treason and plot…
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Johann Friedrich Wilhelm Adolf von Baeyer
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Barbituric Acid
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Audience Survey Question ANSWER THE QUESTION ON BLUE SCREEN IN ONE MOMENT
Where do barbiturates get their name? •
In honor of Adolf von Bayer’s girlfriend, Barbara
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The urea first used was concentrated from the urine of a dog named Barbara
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The molecule was discovered on the day of the Feast of Saint Barbara
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The urea first used was concentrated from the urine of a Munich barmaid named Barbara
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Saint Barbara
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Barbital Josef von Mering
Hermann Emil Fischer
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Audience Survey Question ANSWER THE QUESTION ON BLUE SCREEN IN ONE MOMENT
Where does the drug Veronal get its name? •
The drug makes you sleepy, and the city of Verona was considered the most tranquil city in Europe
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Von Mering was on vacation in Verona when he got a telegram from Emil Fischer about the drug’s discovery
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Stems from the Latin root “verum” meaning ‘truth’
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The discovery was celebrated over a bottle of wine made from veron grapes
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Veronal
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Obtained from the site http://www.wellcomeimages.org/ and is under the Creative Commons Attribution only license CC BY 4.0
Audience Survey Question ANSWER THE QUESTION ON BLUE SCREEN IN ONE MOMENT
Which celebrity’s death was NOT due to barbiturate overdose? •
Judy Garland
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Jimi Hendrix
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Michael Jackson
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Marilyn Monroe
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None. All of the above died of barbiturate overdose.
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Nembutal
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Pentothal
Transferred from Flickr by User:JohnnyMrNinja using flickr2commons
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Liquid Anaesthetics
Credit: Science Museum, London. Wellcome Images
[email protected] http://wellcomeimages.org
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WWII
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Narcoanalysis
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This is an image from the Nationaal Archief, the Dutch National Archives, and Spaarnestad Photo, donated in the context of a partnership program.
Audience Survey Question ANSWER THE QUESTION ON BLUE SCREEN IN ONE MOMENT
Which of the following is true about “Truth Serum”? •
The term "truth serum" came onto the scene in the 1920’s.
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Confessions of guilt under the influence of truth serum were ruled in admissible in US courts in 1963.
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Scopolamine, Pentothal, Sodium Amytal, and Ethyl Alcohol have all been used as “truth serums.”
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“Truth serums” don’t insure the truth but instead disorient and create positive feelings that make lying more difficult.
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All of the above are true. 26
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Truth Serum
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Sodium Amytal
Credit: Science Museum, London. Wellcome Images
[email protected] http://wellcomeimages.org
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Lethal Injection
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Hospira
This file is licensed under the Creative Commons Attribution 3.0 Unsupported license. Attribution: Acherubini2020 at en.wikipedia
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Propofol
"Ampoule prefilled JPN" by ignis - Own work. Licensed under CC BY-SA 3.0 via Wikimedia Commons https://commons.wikimedia.org/wiki/File:Ampoule_prefilled_JPN.jpg#/media/File:Ampoule_prefilled_JPN.jpg
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“From Truth Serum to Anesthesia: The Discovery and Uses of Sodium Thiopental”
Michael Matson Reservoir Engineer, Kinder Morgan CO2
David Harwell Asst. Director of Industry Member Programs, ACS
Slides available now! Recordings will be available to ACS members after one week
www.acs.org/acswebinars Contact ACS Webinars at
[email protected] 32
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05/11/2015
How has ACS Webinars benefited you?
®
“Advanced Pyrotechnics 2 was a great presentation. It was well organized and covered a good deal of very fundamental key descriptions about pyrotechnics. I really appreciated Chris Mocella emphasizing clubs and pyrotechnics organizations.”
Paul Smith, Director of Lecture Demonstrations, Purdue University Vice President, Pyrotechnics Guild International
Be a featured fan on an upcoming webinar! Write to us @
[email protected] 33
facebook.com/acswebinars @acswebinars youtube.com/acswebinars
Search for “acswebinars” and connect! 34
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05/11/2015
Benefits of ACS Membership Chemical & Engineering News (C&EN) The preeminent weekly news source.
NEW! Free Access to ACS Presentations on Demand® ACS Member only access to over 1,000 presentation recordings from recent ACS meetings and select events.
NEW! ACS Career Navigator Your source for leadership development, professional education, career services, and much more.
www.acs.org/2joinACS
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®
ACS Webinars does not endorse any products or services. The views expressed in this presentation are those of the presenter and do not necessarily reflect the views or policies of the American Chemical Society.
Contact ACS Webinars ® at
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05/11/2015
®
Upcoming ACS Webinars www.acs.org/acswebinars
Thursday, November 12, 2015
“Chemistry of Addiction” Anthony Rappé, Professor of Chemistry, Colorado State University Darren Griffen, Professor of Genetics, University of Kent
Thursday, November 19, 2015
“Prodrugs in Drug Discovery” John Higgins, Senior Principal Scientist and Network Technology Lead, Merck Nicholas Meanwell, Executive Director, Discovery Chemistry, Bristol-Myers Squibb
Contact ACS Webinars ® at
[email protected] 37
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