Shou-Fu Lu , Binglong Chen , Dave Davey , Laura Dunning , Stefan Jaroch , Karen May , James Onuffer , Gary Phillips , Babu Subramanyam , Jih-Lie Tseng...
Sep 11, 2003 - The recent approval of a new class of drug, known as entry/fusion inhibitor T-20 (Fuzeone)10-13 by the U.S. FDA, has generated hope that it ...
Publication Date (Web): January 6, 2004. Copyright ... a Obtained from Physician's Desk Reference (PDR), 2002.b Sturcutres obtained from http://chembank.med.harvard.edu/bioactives/.c Estimated based on Hypothesis-1. 01/06/2004 ... Citation data is ma
Pharmacophore Models for CCR5 Antagonists: Study ... with Five Marketed CNS Drugs (Negative Control) Known To Target GPCR Receptors Other than. CCR5.
Sep 11, 2003 - Generation of Predictive Pharmacophore Models for CCR5 Antagonists: Study with Piperidine- and Piperazine-Based Compounds as a New Class of HIV-1. Entry Inhibitors. Asim Kumar Debnathâ . Laboratory of Molecular Modeling & Drug Design,
Predictive pharmacophore models were developed for a large series of piperidine- and .... in drug discovery research.37-56 According to a recent report, it costs ...
Mar 9, 2015 - Centre for Computational Natural Sciences and Bioinformatics, International Institute of Information and Technology, Hyderabad 500032, India. â¡ Centre for Molecular Modeling, Indian Institute of Chemical Technology, Hyderabad 500007,
Oct 23, 2007 - Renata Silva , Andreia Palmeira , Helena Carmo , Daniel José Barbosa ... Eduardo E. Chufan , Hong-May Sim , Suresh V. Ambudkar. 2015 .... Wu-Xiong Li , Leping Li , John Eksterowicz , Xuefeng Bruce Ling , Mario Cardozo.
Mar 9, 2015 - The best models are suggested by validating all the models based on their ... A Molecular Dynamics-Shared Pharmacophore Approach to Boost Early-Enrichment Virtual ... Journal of Chemical Sciences 2016 128 (5), 719-732 ... within the myc
Oct 23, 2007 - Significance Analysis and Multiple Pharmacophore Models for Differentiating P-Glycoprotein Substrates. Wu-Xiong Li*, Leping Li, John ...
Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080 ..... while dashed lines show the optimal cutoff (Î = 0.51) to call the ensemble of 598 significant pharmacophores. ...... Catalyst, version 4.9; Accelrys Software Inc.: San
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J. Med. Chem. 2004, 47, 768
Additions and Corrections 2003, Volume 46 Asim Kumar Debnath*: Generation of Predictive Pharmacophore Models for CCR5 Antagonists: Study with Piperidine- and Piperazine-Based Compounds as a New Class of HIV-1 Entry Inhibitors. Page 4512. The double-plus signs in the last column of Table 6 should be single plus signs. The corrected Table 6 is shown below. Table 6. Results of Validation with Five Marketed CNS Drugs (Negative Control) Known To Target GPCR Receptors Other than CCR5
c
a Obtained from Physician’s Desk Reference (PDR), 2002. b Sturcutres obtained from http://chembank.med.harvard.edu/bioactives/. Estimated based on Hypothesis-1.
JM0306071 10.1021/jm0306071 Published on Web 01/06/2004
