book review
Multiparameter flow cytometry in the diagnosis of hematologic malignancies ne (eds), A. Porwit and M. C. Be Cambridge University Press, Cambridge, 2018, ISBN 978-1-107-50383-0. This 230 page, multi-author book gives detailed, comprehensive information on flow cytometric immunophenotyping, starting with methods of analysis and the nature of the antigens studied. Other chapters cover, as would be expected, the application of immunophenotyping in acute leukaemias, B, T and NK neoplasms, myeloma and the increasingly important subject of the detection of minimal residual disease. There are also chapters on myelodysplastic syndromes, diagnosis of Hodgkin lymphoma in lymph nodes (although this would much more often be done by immunohistochemistry) and on reactive conditions that need to be distinguished from haematological neoplasms. The book is sufficiently detailed and authoritative that it will be useful in immunophenotyping laboratories. It is well referenced. Haematology trainees not directly involved in the laboratory practice of immunophenotyping may find there is more technical information that they wish to acquire but the detailed descriptions of scatter plots will make it easy for them to expand their knowledge of the field.
doi: 10.1111/bjh.15463
Some may regret that a distinguished British publisher has chosen to use a curious mixture of USA and British spelling, varying between chapters and sometimes even within a chapter. There are also occasional copy-setting errors (part of one figure appears to have wandered into another). The book is recommended to haematopathologists and haematologists. It complements Leach M, Drummond M and Doig A, Practical Flow Cytometry in Haematology Diagnosis, Wiley-Blackwell, 2013, previously reviewed in this journal. The current book does not relate immunophenotype to cytology as was done in the earlier book but gives considerably more examples of flow cytometry plots. Barbara J. Bain Centre for Haematology, St Mary’s Hospital Campus of Imperial College London, Praed Street, London, W2 1NY
ª 2018 John Wiley & Sons Ltd British Journal of Haematology, 2018, 182, 308
