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EDITOR

HANS NEURATH, University of Washington

Published by the AMERICAN CHEMICAL SOCIETY

1155 16th Street, N.W. Washington, D. C. 20036 ASSOCIATE EDITORS

Milton P. Gordon, University of Washington

BOOKS AND JOURNALS DIVISION

John Κ Crum Director Ruth Reynard Assistant to the Director

Edmond H. Fischer, University of Washington William W. Parson, University of Washington

EDITORIAL ADVISORY BOARD

Charles R. Bertsch Head, Editorial Processing Department D. H. Michael Bowen Head, Journals Department Bacil Guiley Head, Graphics and Production Department Seldon W. Terrant Head, Research and Development Department

Robert H. Abeles, Brandeis University Konrad Bloch, Harvard University Paul D. Boyer, University of California, Los Angeles Ludwig Brand, Johns Hopkins University W. Wallace Cleland, University of Wisconsin Roger D. Cole, University of California, Berkeley Lyman C. Craig, The Rockefeller University Jack Gorski, University of Illinois Irwin C. Gunsalus, University of Illinois Lowell P. Hager, University of Illinois William F. Harrington, Johns Hopkins University F. M. Huennekens, Scripps Clinic & Research Foundation Irving M. Klotz, Northwestern University Daniel E. Koshland, University of California, Berkeley Marian E. Koshland University of California, Berkeley

© Copyright, 1974, by the American Chemical Society. Published biweekly by the American Chemical Society at 20th and Northampton Streets, Easton, Pennsylvania. Second-class postage paid at Washington, D. C., and at additional mailing offices. Manuscripts for publication and correspondence regarding accepted papers should be sent to the Editor, Hans Neurath, University of Washington, Seattle, Washington 98195. Proof, edited manuscripts, and reprint orders should be sent to Editorial Processing Department, American Chemical Society, 20th and Northampton Streets, Easton, Pa. 18042. Head, Charles R. Bertsch. Senior Production Editor: Mari­ anne C. Brogan. Assistant Editors: Patricia A. Bronko and Deborah A.Wilson. Editorial Assistant: Holley A. Stewart. Advertising Office: Centcom, Ltd., 142 East Avenue, Norwalk, Con­ necticut 06851. The American Chemical Society and the Editors of Biochemistry assume no responsibility for the statements and opinions advanced by contributors to this joural.

Edwin G. Krebs, University of California, Davis Michael Laskowski, Jr., Purdue University Albert L. Lehninger, Johns Hopkins University Nelson J. Leonard, University of Illinois Albert S. Mildvan, Institute for Cancer Research, Philadelphia Kivie Moldave, University of California, Irvine Mary Jane Osborne, University of Connecticut William D. Phillips, Du Pont Experimental Station Joanne Ravel, University of Texas Phillips W. Robbins, Massachusetts Institute of Technology Irwin A. Rose, Institute for Cancer Research, Philadelphia Harold A. Scheraga, Cornell University Elliott Shaw, Broohaven National Laboratories S. Jonathan Singer, University of California, San Diego Earl R. Stadtman, National Heart Institute Ignacio Tinoco, Jr., University of California, Berkeley Paul O. P. Ts'o, Johns Hopkins University Bert L. Vallee, Harvard University Κ. Ε. Van Holde, Oregon State University Finn Wold, University of Minnesota Medical School SECRETARY OF THE BOARD

Warren E. C. Wacker, Harvard Medical School

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BIOCHEMISTRY,

V O L . 13,

N O . 8,

1974

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