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770 A · ANALYTICAL CHEMISTRY, VOL. 59, NO. 11, JUNE 1, 1987
the fact that companies continue to bring out innovations based on different physical principles suggests that everybody's not completely happy with what we've got." "The GC/MS interface is so simple to use," adds Richard Browner of Georgia Institute of Technology. "There's essentially nothing to worry about. It just works. People use it day in and day out. And you'd like an LC/MS interface that has the same simplicity of operation." Jack Henion of Cornell University agrees with Fenselau that "thermospray has clearly not established itself as being the answer to all the problems. It solves some of them and it definitely works, but it doesn't address everybody's concerns. So there is still a lot of interest in what options are available." The options available at this year's meeting included the VG Plasmaspray interface, which directs the aerosol from a thermospray unit through a glow discharge located around the
"The important thing is that two companies . . . are sticking their necks out and doing something that I feel very strongly about, and that is the need to obtain EI information from
• m a j o r t e a c h i n g fields • highest d e g r e e e a r n e d • a c a d e m i c rank
Name of cardholder
FOCUS
thermospray probe. The idea is to break up species in the aerosol to provide more structural information. "What people are doing with Plasmaspray," says Browner, "is to try to get structural information out of thermospray, an inherently soft-ionization technique that normally gives Cl-type spectra." An additional option that became available at this year's meeting was Extrel's new ThermaBeam interface, which operates on a principle that is similar to that of the MAGIC (monodisperse aerosol generation) interface originally developed by Richard Browner and Ross Willoughby at Georgia Tech. Browner explains that the MAGIC interface is "basically a desolvation device for eliminating the solvent from LC effluent and getting dry particles into the mass spectrometer ion source area. What apparently happens—we're still investigating the mechanism—is the dry particles go into the ion source
