1720
Biochemistry 1985, 24, 1720-1 727
High-Resolution Proton Nuclear Magnetic Resonance Studies of Human Gastrin Andrew E. Torda,' Graham S. Baldwin,# and Raymond S . Norton*.' School of Biochemistry, University of New South Wales, Kensington, N.S.W. 2033, Australia, and The Ludwig Institute for Cancer Research, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia Received October 1, 1984
ABSTRACT: High-resolution
'Hnuclear magnetic resonance (NMR) spectroscopy at 300 MHz has been
used to study the behavior of human gastrin in aqueous solution. A large number of resonances have been assigned by analysis of one- and two-dimensional N M R spectra and the effects of pH and by comparison with the spectrum of des-
