Determination of 1-Chloro-1-pentene-3-one in 1-Chloro3-ethyl-1 -penten4-yn-3-01
Determination of 2-Pentanol in Mixture with 2-Bromopentane Plus 3-Bromopentane W. H. WASHBURN and M. J. MAHONEY, Abbott laboratories, North Chicago, 111. Slit
Component No.
1
I
A orv Range Accuracy B.1. % % Pts.
1~ Formula
Name 2-Pentanol
CS-25
-
0-5
CbH120
f0.2
(mm) AX or Av
Concn. % v/v length mm
0.044 0.026
25 1.05
-
2.74 ~
-
W. H. WASHBURN and F. A. SCHESKE, Abboft laboratories, North Chicago, 111. I
Component No.!
Calculotion:
Base l i n e 2
Inverted m a t r i r GraphicalX
Relative Absorbances-Analytical
pentene3-one
Calculafion:
2.74~ 5.500
Reference cqmpounds 9 9 +
1 I
CjHs
25
0.5
mL1
Point-
5.93p 21.3
CS-26
Commenfs: This is a differential analysis employing a 25% CHCli SOIUtion of pure 1-chloro-3-ethyl-l-penten-4-yn-3-01 in a 0.5-mm. cell as campensating material, For details see: Washburn, W. H., and Scheske, F. A., Anal. Chem. 29, 3 4 6 (1957). Relative absorbances are given as the slope of the Beer's law concentration curves used expressed in terms o f absorbance per 100% of constituent.
Determination of Chlorcyclizine and Mixtures
Pramoxine in cs-28
W. H. WASHBURN, Abbott laboratories, North Chicago, 111.
Concn.
%
1
length
0-5
j
mm *0.05
13.7 Adjacent shoulders
i
0.552 0.098
100
0.035 2
~
Pramoxine
Insfrumenf: Perkin-Elmer Model 21, NaCl prism Sample Phase: Full strength Cell Windows: NaCl Absorbance Measurement: Colculotion:
I
Reference compounds 9 9 +% pure
Maferiol Purity:
% pure
Slif
Toluene
0.165 0.055
Successive approx.-
1
W. H. WASHBURN and F. A. SCHESKE, Abbott laboratories, North Chicago, 111.
~
Base I i n e X
Inverted m a t r i r Gro p h i c a l X
ComponentlX
Determination of Toluene in 1-Chloro-1-pentene-3-one
1
1
' 5.93 15.651 6.10
Relative Absorboncesa-AnalyticaI Matrix:
Commenfs: No interferences from 2- or 3-bromopentane encountered at 2.74 microns. Absorption at 2.74 microns arises from free 0 - H stretching vibration. Base line should b e drawn from short wave length shoulder parallel ta abscissa of chart paper inasmuch as slight H bonding in higher part of range causes same drop-off in long wave length shoulder.
No.1
0-1
~
Cell Windows: NaCl Absorbance Measurement:
Poinf-
Matrix:
1
Component Nome Formula
1
=tO.O2
Instrument: Perkin-Elmer Model 2 1, NaCl prism Sample Phase: Solution in CHCls
Successive approx.-
ComponentlX
Material Purity:
Nome 1 Formula~ --I
7 1 1-Chloro-1- 1 CsHjCIO
Instrument: Perkin-Elmer Model 21, NaCl prism Sample Phase: Solution in CSz Cell Windows: NaCl Absorbance Measurement:
CS-27
Base I i n e X
Inverted m a t r i r Gra p h i c a l X
Relofive Absorbances'-Analyficol Component/X 1
Point-
Successive apprax.-
Mofrix:
1
C1jH17N03 1 9 0 - 1 1 0
I
1
=t2
18.97
~
0:447 0 094
I
30.0
0.55
lnsfrument: Perkin-Elmer Model 12C, NaCl prism Sample Phase: Solution in CHC13 Cell Windows: NaCl Absorbance Measuremenf: Base lineCalculation: Inverted m a t r i r GraphicalX
P o i n t X Successive appro*.-
Relofive Absorbancesa-AnolyticoI Matrix: 13.7~ 10.0
Maferial Purity: Reference compounds 99+% pure Commenfs: Automatic slit programing used because o f rapid fall In source energy in this region.
Component/X
7.74P
8.97P
1
0.344 0.133
0.055 0.430
2
Maferiol Purity: Reference compounds 9 9 +% pure Commenfs: Ratio o f chlorcyclizine to pramoxine is 2 to 1 in a typical preparation.
a Relative absorbances are given as the slope of the Beer's law concentration curves used expressed in terms o f absorbance per 100% of constituent.
a Relative absorbances ore given os the slope of the Beer's low concentration curves used expressed in terms o f absorbance per 100% of constituent.
These data represent standard publication and submission is open to an one in accordance with regulations of ANALYTICAL CHEMISTRY.The Cobgnta Society is acting only as an aid to the Journal.
To standardiee procedures ANALYTICAL CHEMIBTRY requests that material be sent in quintuplicate to the chairman of the review committee: Robert C. Wilkerson, Celanese Corp. of America, Post Office Box 8, Clarkwood, Tex.
304
ANALYTICAL CHEMISTRY
