Introducing Our Authors Cite This: ACS Chem. Biol. 2017, 12, 2916−2917
■
ASHISH GUPTA
Education: Lebanese University, Lebanon, B.A. Chemistry; Claude Bernard University, France, M.S. Synthesis, Catalysis, and Sustainable Chemistry; University of Nice-Sophia Antipolis, Ph.D. Organic Chemistry and Biological Applications, Advisor: Prof. Alain Burger Current Position: Postdoctoral Fellow and instructor at University of Strasbourg, Institute of Physics and Chemistry of Materials (IPCMS), in collaboration with Kyoto University, Japan Nonscientific Interests: Traveling, sports, music, and discovering new cultures My early research involved metal catalysis and C(sp3)-H activation. During the course of my Ph.D., I was interested in the development of new methodologies and versatile routes to synthesize fluorescent probes and in advanced uses of the designed sensors in biological applicationsparticularly in sensing nucleic acids interactions (DNA) and membrane lipids. I am currently working to develop organic liquid materials for new generations of solar cells and organic light emitting diodes (OLEDs). In this paper, we report the colorimetric sensing of the lipid ordered and disordered phases in biomembranes with exquisite selectivity, using a fluorogenic probe based on an environmentally sensitive fluorenyl conjugate and propiolyl linker that conserves the specific spectroscopic features of the core dye. (Read Shaya’s article DOI: 10.1021/acschembio.7b00658.)
Image courtesy of Ashish Gupta.
Education: Shri Mata Vaishno Devi University, B.Tech. Industrial Biotechnology; Amity University, M.Tech. Biotechnology; Louisiana State University, Ph.D. Biochemistry, Advisor: Dr. Anne Grove Current Position: Postdoctoral Fellow, Laboratory of Infectious Diseases, National Institute of Allergic and Infectious Diseases, National Institute of Health, Bethesda, MD, Advisor: Dr. Joseph Marcotrigiano Nonscientific Interests: Traveling and exploring new places, camping, music, driving My Ph.D. project was mainly focused on understanding the responses of host-derived signals (urate and reactive oxygen species) in Burkholderia thailandenesis. In this project, we wanted to understand the impact of urate on B. thailandenesis. MftR is a B. thailandenesis-encoded multiple antibiotic resistance regulator (MarR) homologue. To understand the impact of urate and MftR on B. thailandenesis, we performed RNA sequence analysis. Our data of RNA sequence analysis showed that MftR is a master regulator, which represses various biosynthetic gene clusters and control genes responsible for survival in a host environment. Our data from this RNA sequence study would not only help to understand the activation of gene regulatory networks but also will pave the way for the isolation of new therapeutics. (Read Ashish’s article DOI: 10.1021/acschembio.7b00681.) JANAH SHAYA
■
■
GUANNAN WANG
Image courtesy of Chathura Wijesinghege.
Education: Henan Agricultural University, China, B.S. Biotechnology, 2012 Current Position: Louisiana State University, Department of Biological Sciences, Ph.D. Candidate, Advisor: Dr. Maheshi Dassanayake Nonscientific Interests: Badminton, volleyball, traveling, music My research focuses on investigating plant adaptations to boron toxicity. I use a model extremophyte, Schrenkiella parvula, which is extremely tolerant of high boron levels in its native soils, to understand the molecular and genetic mechanisms that enable Published: December 15, 2017
Image courtesy of Dr. Janwa ElMaiss.
© 2017 American Chemical Society
2916
DOI: 10.1021/acschembio.7b01037 ACS Chem. Biol. 2017, 12, 2916−2917
ACS Chemical Biology
Introducing Our Authors
plants to minimize cellular toxicity due to high boron stress. I include the boron stress sensitive model plant Arabidopsis thaliana in my research as a comparator species to contrast the transcriptomic response of S. parvula. I am currently characterizing the transcriptomic responses to excess boron in the two-target species and validating a hypothesis developed based on the transcriptomic analysis using targeted transgenic lines created for S. parvula. (Read Guannan’s article DOI: 10.1021/ acschembio.7b00681.)
2917
DOI: 10.1021/acschembio.7b01037 ACS Chem. Biol. 2017, 12, 2916−2917
