Invited Manuscript - Organic Process Research & Development (ACS

12 Feb 2014 - It is our pleasure to introduce an invited contribution from Professor ... for process chemists seeking alternative conditions for hydro...
0 downloads 0 Views 101KB Size
Editorial pubs.acs.org/OPRD

Invited Manuscript

I

t is our pleasure to introduce an invited contribution from Professor Douglas W. Stephan of the University of Toronto, featuring work on hydrogenations using “Frustrated Lewis Pairs”. Hydrogenations remain one of the most utilized synthetic transformations in Process Chemistry. Historically, precious metals such as palladium, platinum, rhodium, and ruthenium have been utilized to catalyze these reactions. This account highlights the progress made in professor Stephan’s laboratories on using frustrated Lewis pairs as metal-free catalysts for hydrogenations. The synthetic method presented is proving to be fairly general, as the substrate scope is rapidly expanding. We believe that, while these catalysts are gaining popularity in many laboratories, they will also find utility for process chemists seeking alternative conditions for hydrogenations. We thank Professor Stephan for his contribution to OPRD.



Stéphane Caron

AUTHOR INFORMATION

Corresponding Author

stephane.caron@pfizer.com Notes

Views expressed in this editorial are those of the author and not necessarily the views of the ACS.

Published: February 12, 2014 © 2014 American Chemical Society

384

dx.doi.org/10.1021/op400326j | Org. Process Res. Dev. 2014, 18, 384−384