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Low-level Prenatal Mercury Exposure in North China: An Exploratory Study of Anthropometric Effects Langbo Ou, Cen Chen, Long Chen, Huanhuan Wang, Tianjun Yang, Han Xie, Yindong Tong, Dan Hu, Wei Zhang, and Xuejun Wang Environ. Sci. Technol., Just Accepted Manuscript • DOI: 10.1021/es5055868 • Publication Date (Web): 02 May 2015 Downloaded from http://pubs.acs.org on May 7, 2015
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Environmental Science & Technology
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Low-level Prenatal Mercury Exposure in North China: An
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Exploratory Study of Anthropometric Effects
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Langbo Ou1, Cen Chen1, Long Chen1, Huanghuang Wang1, Tianjun Yang1, Han Xie1, Yindong
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Tong1, Dan Hu1, Wei Zhang2*, Xuejun Wang1*
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Environmental Sciences, Peking University, Beijing, 100871, China
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100872, China
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Corresponding authors:
Ministry of Education Laboratory of Earth Surface Process, College of Urban and
School of Environment and Natural Resources, Renmin University of China, Beijing,
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Wei Zhang. School of Environment and Natural Resources, Renmin University of China,
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Beijing, 100872, China. Tel: +86-10-62756122. E-mail:
[email protected] 12
Xuejun Wang. Ministry of Education Laboratory of Earth Surface Processes, College of
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Urban and Environmental Sciences, Peking University, Beijing, 100871, China. Tel:
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+86-10-62759190. E-mail:
[email protected] 15
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ACS Paragon Plus Environment
Environmental Science & Technology
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Abstract
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In order to investigate anthropometric effects of mercury (Hg) exposure, we examined the
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status of human prenatal exposure to Hg species, including total mercury (THg),
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methylmercury (MeHg) and inorganic mercury (IHg), in North China, as well as their
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potential effects on fetal and infant growth. Hg concentrations in various bioindicators were
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measured from 50 Chinese women and newborns in 2011. The participants were followed for
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12 months to collect anthropometric information. Linear and two-level regression analyses
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were performed to determine the associations between Hg levels and body growth. The
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geometric mean levels of THg in the placenta, cord blood, fetal hair, and maternal blood, hair
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and urine were 25.88 µg/kg dry wt, 2.73 µg/L, 572.98 µg/kg, 2.29 µg/L, 576.54 µg/kg, and
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0.58 µg/g creatinine, respectively. Nearly 100% of Hg presented as IHg in urine, and the
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percentage of IHg in other bioindicators was 14.86%-48.73%. We observed significantly
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negative associations between Hg levels in some matrixes and anthropometry of neonates
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(weight and height) and infants (height) (p
