JANUARY 1, 1992 VOLUME 64 NUMBER 1 ANCHAM Aua„ 64(1) 1A-62A/1-112 (1992) eu,tau | S S N 0003-2700 Registered in U.S. Patent and Trademark Office; ©Copyright 1991 by the American Chemical Society
Analytical CHEMISTRY
EDITOR: ROYCE W. MURRAY ASSOCIATE EDITORS: Catherine C. Fenselau, Georges Guiochon, Robert A. Osteryoung, Edward S. Yeung Editorial Headquarters 1155 Sixteenth St., N.W. Washington, DC 20036 Phone:202-872-4570 Telefax: 202-872-4574 Bitnet: rmh96@cas Internet:
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INSTRUMENTATION
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On the cover. Electrochemistry o n line w i t h m a s s spectrometry provides chemical information about electrochemically generated species with excellent time resolution. Richard A. Yost and Anna Brajter-Toth of the University of Florida and Kevin J. Volk of Bristol-Meyers Squibb discuss how this technique can be used to directly monitor reactants, shortlived intermediates, and products of electrochemical reactions as a function of electrode potential
A/C INTERFACE
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M a c h i n e l e a r n i n g techniques enable researchers to more fully interpret data and avoid the bottlenecks encountered in t r a d i tional expert systems developm e n t . E. D. S a l i n of McGill University and Patrick H. Winston of the Massachusetts Institute of Technology describe the use of machine learning methods to determine the source of instrumental problems encountered when analyzing a set of water samples
Kathleen Strum Editorial Assistant: Joanne Mullican Journals Dept., Columbus, Ohio Associate Head: Marianne Brogan Editorial Office Manager: Mary E. Scanlan Journals Editing Managers: Kathleen E. Duffy, Joseph E. Yurvati Assistant Editors: Stephanie R. Harrell, Diane E. Needham Advisory Board: Michelle V. Buchanan, M. Bonner Denton, William S. Hancock, Joel M. Harris, Timothy D. Harris, Franz Hillenkamp, Dennis C. Johnson, Richard A. Keller, Philip D. LaFleur, Alan G. Marshall, John F. Rabolt, Geraldine Richmond, Ralph Riggin, Debra R. Roli¬ son, Shigeru Terabe, Michael Thompson Ex Officio: Charles L. Wilkins Instrumentation Advisory Panel: Daniel W. Armstrong, Anna Brajter-Toth, Thomas L. Chester, Raymond E. Clement, Norman J. Dov¬ ichi, Jack D. Henion, John W. Olesik, Dallas L. Rabenstein, Brenda R. Shaw Publications Division Director: Robert H. Marks Journals: Charles R. Bertsch Published by the AMERICAN CHEMICAL SOCIETY 1155 Sixteenth Street, N.W. Washington, DC 20036 (202) 872-4600 TDD (202) 872-8733 FAX (202)872-4615
UPCOMING RESEARCH
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EDITORIAL
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A few n e w things. As 1992 begins, the JOURNAL sports some immediate changes, including a new Table of Contents and an Upcoming Research section. Within a few months, manuscripts will be submitted for review and evaluation by the Editor and Associate Editors in procedures generally parallel to those traditionally exercised by other ACS journals
NEWS
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Joel M. Harris, Franz Hillenkamp, Dennis C. Johnson, Richard A. Keller, Géraldine Richmond, Ralph Riggin, and Charles L. Wilkins join ANALYTICAL CHEMISTRY'S Advisory Board. · 1992 Pittsburgh Conference Memorial National College Grants Awards. · Hirschfeld Award nomin a t i o n s . · Procter & Gamble s u m m e r jobs
MEETINGS
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The 4th International S y m p o s i u m o n High-Performance Capillary Electrophoresis (HPCE '92) will be held Feb. 9 - 1 3 at the RAI Congress Centre in Amsterdam, The Netherlands. · Comprehensive listing of 1992 conferences. · Call for papers
NEW PRODUCTS & MANUFACTURERS' LITERATURE
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ANALYTICAL CHEMISTRY, VOL. 64, NO. 1, JANUARY 1, 1992 · 5 A
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Analytical® CHEMISTRY
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ARTICLES Interactive Control of Pulsed Field Gel Electrophoresis via Real Time Monitoring David A. McGregor and Edward S. Yeung*
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Dual-Field and Flow-Programmed Lift Hyperlayer Field-Flow Fractionation S. Kim Ratanathanawongs and J. Calvin Giddings*
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Liquid Chromatographic Retention Behavior of Polystyrene Homopolymers on a C 4 , Bimodal Pore Diameter, Reversed-Phase Column DavidM. Northrop, DanielE. Martire', andR.P.W. Scott Absorbance Study of Liquid-Core Optical Fibers in Spectrophotometry Wang Wef, He Qushe, Wang Tao, Fen Minzhao, Liao Yuanmin, and Ran Gouxia Analysis of the Surface Heterogeneity of Different Samples of Aluminum Oxide Ceramic Powders Jeffry Roles, Kevin McNerney, and Georges Guiochon* Study of the Surface Heterogeneity of Chromatographic Alumina Jeffry Roles and Georges Guiochon* Nitroprusside and Methylene Blue Methods for Silicone Membrane Differentiated Flow Injection Determination of Sulfide in Water and Wastewater Vlastimil Kuban, Purnendu Κ Dasgupta*', and John N. Marx
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Multichannel Electrochemical Detection with a Microelectrode Array in Flowing Streams AtsushiAoki, Tomokazu Matsue*", andlsamu Uchida
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Atomic Emission Detection for Supercritical Fluid Chromatography Using a Moderate-Power Helium Microwave-Induced Plasma Gregory K. Webster and Jon W. Carnahan*
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Planar Waveguide Immunosensor with Fluorescent Liposome Amplification Steven J. Choquette*, Laurie Locascio-Brown, and Richard A. Durst
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Atmospheric Pressure Ion-Sampling System for Liquid Chromatography/Mass Spectrometry Analyses on a Benchtop Mass Spectrometer Kevin L. Duffin, Timothy Wachs, and Jack D. Henion* Chirality Distributions through Lifetime Resolution in Fluorescence-Detected Circular Dichroism and Circularly Polarized Luminescence: A Theoretical Treatment Lei Geng and Linda B. McGown* Formation of Multiply Charged Ions of the Oligopeptide A r g - A r g - A r g by Electrospray Ionization Kenzo Hiraoka* and Ichiro Kudaka
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continued on p. 9 A
ACS membership information: Lorraine Bowlin (202-872-4567)
ANALYTICAL CHEMISTRY, VOL. 64, NO. 1, JANUARY 1, 1992 · 7 A
Analytical® CHEMISTRY Editorial Information Instructions for authors of AC RESEARCH are published in the January 1 issue, p. 107. Guidelines for the INSTRUMENTATION, REPORT, ANALYTICAL APPROACH, and A/c INTERFACE features are
available from the Washington editorial office. Please consult these instructions and guidelines prior to submitting a manuscript for consideration for publication. Manuscripts for publication (4 copies of text and illustrative material) should be submitted to ANALYTICAL CHEMISTRY at the ACS Washington ad-
dress. Please include a signed copyright status form; a copy of this document appears on p. 111 of the January 1 issue. Correspondence regarding manuscripts under review should be directed to the Washington editorial staff; correspondence regarding accepted papers and proofs should be directed to the Journals Dept. in Columbus at the address below. For individual reprints of AC RESEARCH or A-page articles, please contact the authors directly. Bulk reprints of individual articles are available from ACS. For information, write or call the Distribution office at the ACS Washington address (202-872-4539; fax 202-872-4615). ACS Division of Analytical Chemistry Chair, Charles Wilkins (714-787-3518) Secretary, Sarah Rutan (804-367-1298) ACS Information Library Services Education Division Meetings Dept. Member Services Employment Services Public Outreach
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Multiply Charged Negative Ions by Electrospray Ionization of Polypeptides and Proteins Joseph A. Loo, Rachel R. Ogorzalek Loo, Karen J. Light, Charles G. Edmonds, and Richard D. Smith* Determination of Free Magnesium Ion Concentration in Aqueous Solution Using 8-Hydroxyquinoline Immobilized on a Nonpolar Adsorbent Gocool Persaud and Frederick F. Cantwell*
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Four-Layer Theory for the Acoustic Shear Wave Sensor in Liquids Incorporating Interfacial Slip and Liquid Structure Wendy C. Duncan-Hewitt* and Michael Thompson
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Correction. Statistical Theory of Spot Overlap in Two-Dimensional Separations Joe M. Davis
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Manuscript Requirements
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Ethical Guidelines to Publication of Chemical Research
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Copyright Status Form
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Author Index
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Supplementary material is noted in the table of contents with a • . It is available as photocopy ($10.00 for up to 3 pages and $1.50 per page for additional pages, plus $2.00 for foreign postage) or as 24X microfiche ($10.00, plus $1.00 for foreign postage). Canadian residents should add 7% GST. See supplementary material notice at end of journal article for number of pages. Orders must state whether for photocopy or for microfiche and give complete title of article, names of authors, journal, issue date, and page numbers. Prepayment is required and prices are subject to change. Order from Microforms & Back Issues Office at the ACS Washington address. The paper used in this publication meets the minimum requirements of American National Standard for Information Sciences—Permanence of Paper for Printed Library Materials, ANSI Z39.48-1984. Journals Department American Chemical Society 2540 Olentangy River Road P.O. Box 3330 Columbus, OH 43210 614-447-3600, Ext. 3171 TELEX 6842086; FAX 614-447-3745 Member & Subscriber Services American Chemical Society P.O. Box 3337 Columbus, OH 43210 614-447-3776 800-333-9511 Advertising Office: Centcom, Ltd., 500 Post Road East, Westport, CT 06880 The American Chemical Society and its editors assume no responsibility for the statements and opinions advanced by contributors. Views expressed in the editorials are those of the editors and do not necessarily represent the official position of the American Chemical Society.
ANALYTICAL CHEMISTRY, VOL. 64, NO. 1, JANUARY 1, 1992 · 9 A
