Model Glucostat &LOWE, H. J.,J. Chem.Educ., 32,304A (19%). In an interconnected assembly consisting of a series of flasks, tubes, valves, and other equipment, the n~avernentof liquid through these vessels is manually manipulated to illustrate the mechanisms by which glucose is transferred across cell tnemhranw against a concentration gradient. Intestinal ahsorption oi glucose, postprandial hyprrglycemia, the role of adenosine triphosphate, hyperinsulinism, hypoadrenalism, glycosurin, and other similar conditions can he simulated in the appsratus. Questions:
Although the construction and consequent study of the operation of this model would be valuable for any interested student, such a project would not qualify as an example of the
kind of work this series has encouraged, because no lahoratorjinvestigation is necessary. However, the construction of this model could serve as the starting point for a laboratory investigation. Far example, does the model accurately simulate the phenomena. associated with the intestinal absorption of glucose, with hyperinsulinism, or other condition as determined from n study of these in vivo or in vilro? Can yon construct a similar model, illustrating a different. biochemical system, from your studies of that system in Ishoratory animals? Show, by means of a model, based on your lahorstory investigations, the phenomena associated with a selected series of biochemical reactions that oecnr in a living plant.
Volume 38, Number 9, September 1961
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