Molecular Basis of HIV-1 Protease Drug Resistance - American

Molecular Basis of HIV-1 Protease Drug Resistance: Structural

Rieko Ishima, Paul T. Wingfield, Stephen J. Stahl, Joshua D. Kaufman, and Dennis A. Torchia ... Paul J. Ala, Edward E. Huston, Ronald M. Klabe, Prabhakar K. Jadhav, .... Speranta Avram , L. Movileanu , D. Mihailescu , Maria-Luiza Flonta.

Molecular Basis of HIV-1 Protease Drug Resistance: Structural

Paul J. Ala, Edward E. Huston, Ronald M. Klabe, Denise D. McCabe, Jodie L. Duke, Christopher J. Rizzo, Bruce D. Korant, Richard J. DeLoskey, Patrick Y. S. ...

4A Serine Protease Drug-Resistance

Jan 10, 2013 - Computational methods of modeling proteinâligand interactions have gained widespread application in modern drug discovery. In continuum solvation-based methods of binding affinity estimation, limited description of solvent environmen

4A Serine Protease Drug-Resistance

Jan 10, 2013 - Department of Biology, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore 54792, ...

Molecular Basis of Resistance to HIV-1 Protease ... - ACS Publications

ABSTRACT: The binding thermodynamics of the HIV-1 protease inhibitor acetyl pepstatin and the substrate. Val-Ser-Gln-Asn-Tyr-Pro-Ile-Val-Gln, corresponding ...

Molecular Basis of Resistance to HIV-1 Protease Inhibition: A

Molecular Basis of Resistance to HIV-1 Protease Inhibition: A Plausible Hypothesis. Irene Luque, Matthew J. Todd, Javier GÃ³mez, Nora Semo, and Ernesto ...

Molecular Basis of HIV-1 Protease Drug ... - ACS Publications

Paul J. Ala, Edward E. Huston, Ronald M. Klabe, Denise D. McCabe, Jodie L. ... Bruce D. Korant, Richard J. DeLoskey, Patrick Y. S. Lam, C. Nicholas Hodge, ...

Molecular Basis for Differential Patterns of Drug Resistance in

Nov 7, 2016 - Neuraminidase (NA) inhibitors are used for the prevention and treatment of influenza A virus infections. Two subtypes of NA, N1 and N2, predominate in viruses that infect humans, but differential patterns of drug resistance have emerged

Thermodynamic Basis of Resistance to HIV-1 Protease Inhibition

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Exploring the Drug Resistance of HCV Protease - The Journal of

Jun 21, 2017 - Hepatitis C virus (HCV) currently affects several million people across the globe. One of the major classes of drugs against HCV inhibits the NS3/4A protease of the polyprotein chain. Efficacy of these drugs is severely limited due to

Molecular Basis of HIV-1 Protease Drug Resistance - American

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