Molecular recognition. 2. Molecular recognition of amino acids: two

J . Am, Chem. Soc. 1988, 110, 4016-4011

4076

Table I. Stereoselection of Cycloadditions of C-5 Substituted Cvclomntadienes

Molecular Recognition of Amino Acids: Two-Point Fixation of Amino Acids with Bifunctional Metalloporphyrin Receptors * Yasuhiro Aoyama,* Atsushi Yamagishi, Masumi Asagawa, Hiroo Toi, and Hisanobu Ogoshi*

entrv

comDd

X

a b

1 2 2 3

SH SMe SMe SOMe S02Me OH OMe NHAc NHAc NH2 H

C

d e

4

f

5

g

6 7 7 8 9

h i j

k

reaction time' 3h 27.5 h 46 h 48 h 9 days