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Agricultural and Environmental Chemistry
Potential high value conjugated linolenic acids (CLnA) in melon seed waste Dong Hao Wang, Zhen Wang, Kim Phuong Le, J. Raven Cortright, Hui Gyu Park, Herbert J. Tobias, and J. Thomas Brenna J. Agric. Food Chem., Just Accepted Manuscript • DOI: 10.1021/acs.jafc.9b04744 • Publication Date (Web): 29 Aug 2019 Downloaded from pubs.acs.org on August 30, 2019
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Journal of Agricultural and Food Chemistry
Potential high value conjugated linolenic acids (CLnA) in melon seed waste
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Dong Hao Wanga,b, Zhen Wanga,b, Kim Phuong Lea, J. Raven Cortrighta, Hui Gyu Parka, Herbert
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J. Tobiasa*, J. Thomas Brennaa,b,c*
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a. Dell Pediatric Research Institute, Depts of Pediatrics, of Chemistry, and of Nutrition,
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University of Texas at Austin, 1400 Barbara Jordan Blvd, Austin, TX, United States
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b. Department of Food Science, Cornell University, Ithaca, NY, United States
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c. Division of Nutritional Sciences, Cornell University, Ithaca, NY, United States
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*Corresponding author address. Dell Pediatric Research Institute, University of Texas at Austin,
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1400 Barbara Jordan Blvd, Austin, TX 78723. Tel: 512-495-5249
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E-mail address:
[email protected] (J. T. Brenna);
[email protected] (H. J.
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Tobias)
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[email protected] (D. H. Wang),
[email protected] (Z. Wang),
[email protected] (K. P.
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Le),
[email protected] (J. R. Cortright),
[email protected] (H. G. Park)
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Submitted to JAFC, August 2019
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1 ACS Paragon Plus Environment
Journal of Agricultural and Food Chemistry
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Abstract
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Conjugated linolenic acids (CLnAs) are natural phytochemicals with known and potential
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bioactivities in mammals. Established CLnA sources are limited to a few common fruit seeds,
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notably pomegranate seeds and cherry pits, and the search for alternatives is impeded in part
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by cumbersome methods for reliable measurement. We investigated CLnA contents in lower
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value fruit seeds with a recently available facile mass spectrometry method enabling positive
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identification and quantitative analysis. We report for the first time detection of CLnAs in
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cantaloupe and honeydew seeds at levels of 2 mg CLnA/g seed kernel. Based on the combined
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waste stream for these muskmelons of about 1.4 billion pounds in USA annually, we estimate
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that the available CLnAs amount to 37.5 tons, similar to cherry pits. Our results suggest
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potential enhanced economic value of a specific class of bioactives that may be extracted from
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discarded food processing waste.
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