The Synthesis and Antitumor Activity of Certain Compounds Related to 4-Aminopyrazolo[3,4-d]pyrimidine. Edward Y. Sutcliffe , K. Y. Zee-Cheng , C. C. C...
displacement of the chlorine atom in XI resulted in the preparation of a large number of 6-alkylpyrazolo [3,4-d]pyrimidines substituted in position 4. The disco~ery ...
viously described for pyridoxali X series of nine solutions. 0.5 M in valine of PH 8.3 t o 12 and ionic strength 0.5 was employed. PK~RP for the glycine imine was ...
Potential Purine Antagonists. IV. Synthesis of Some 9-Methyl-6-substituted-purines1. Roland K. Robins, and Hsi Hu Lin. J. Am. Chem. Soc. , 1957, 79 (2), ...
May 1, 2002 - Robert J. Rousseau , Roland K. Robins , Leroy B. Townsend. Journal of the ... Frank B. Howard and Charles A. Dekker. Biochemistry 1967 6 ...
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Potential Purine Antagonists. XI. Synthesis of Some 9-Aryl(alkyl)-2,6-disubstituted. Purines. By Henry C. Koppel and Roland K. Robins1. Received November 30 ...
phy, to R. C. Landwehr and Mrs. I. R. Stuart for carrying out some of the physical measurements cited, and to G. E. Secor for the microchemical analyses.
Department of Chemistry, New Mexico Highlands University]. Potential Purine Antagonists. I. Synthesis of Some 4,6-Substituted. Pyrazolo [3,4-d] pyrimidines1.
May 1, 2002 - Edward Y. Sutcliffe, K. Y. Zee-Cheng, C. C. Cheng, and Roland K. Robins. Potential Purine Antagonists. XXXII. The Synthesis and Antitumor ...
Various structural changes of the natural purines have resulted in several potent antagonists in bio- logical systems.2 Of special interest are the anti-.
FEBRUARY
1955
191
POTENTIAL PURINE ANTAGONISTS. VI1
[CONTRIBTiTION FROM
THE
DEPARTMENT
O F CHEMISTRY,
NEWMEXICO HIGHLANDS UNIVERSITY]
Potential Purine Antagonists VII. Synthesis of 6-Alkylpyrazolo[3,4-d]pyrimidines1~*" C. C. CHESG