DETECT AND QUANTITATE ANTIBIOTICS AT TRACE LEVELS 0.18 ppm TETRACYCLINE · HCI 0. 1 ^ ACETATE BUFFER, pH 4
1 ppm STREPTOMYCIN SULFATE 0.1 Μ Να OH, .001 Μ Ε OTA
0.15 ppm CHLORAMPHENICOL 0.1 M ACETATE BUFFER, pH 4
SISNAL
20 nA
f -0.8
1 -0.9
ι —1.0
ι -1.1
2 0 nA
2 0 nA
ι -1.2
ι -1.3
1T -1.4-0.1
i -0.2
l
l
I
-0.3 -0.4 -0.5 POTENTIAL [ E v i i c e ]
I -0.6
^ Ι -0.7-1.2
ι
ι
ι
1
-1.3
-1.4
-1.5
-1.6
ι -1.7
q -1.8
DIFFERENTIAL PULSE POLAROGRAPHY, DROPPING MERCURY ELECTRODE PAR MODEL 174 POLAROGRAPHIC ANALYZER
For example, the above data indicate how the PAR1" Model 174 Polarographic Analyzer can accurately de termine Tetracycline Hydrochloride, Chloramphenicol, and Streptomycin Sulfate. Differential pulse polarography was the technique employed, allowing detection of very low levels of these materials, even in the presence of interfering substances. But if you're not interested in detecting antibiotics, it's important to note that the 174 can analyze hundreds of different materials as well, including organics, in organics and trace metals. The PAR™ Model 174 Polarographic Analyzer is the only instrument in its price range to provide this capa bility. Its part-per-billion sensitivity permits accurate simultaneous qualitative and quantitative analyses to be performed. Low initial and operating costs and ease of operation make this the instrument of choice where
Ρ' A
measurements must be performed quickly and easily. These features have been important factors in appli cation of the 174 in the analysis of pharmaceuticals, pollutants, metallurgical samples and a broad variety of analytes. Techniques possible include dc, pulse and differen tial pulse polarography, stripping analyses, differential pulse stripping analysis and linear sweep voltammetry. Accessories permit dual cell differential opera tion, ac polarography and other useful techniques. A complete line of cells and electrodes is also available. Price of the 174 is $2250 including mechanical drop timer. Contact P.A.R. for the latest information about how this versatile instrument can improve your ana lytical results. Phone (609) 452-2111 or write Princeton Applied Research Corporation, Dept. H, P.O. Box 2565, Princeton, New Jersey 08540.
PRINCETON APPLIED RESEARCH CORPORATION
R CIRCLE 1 4 6 O N READER SERVICE CARD
44 A .
ANALYTICAL CHEMISTRY, VOL. 44, NO. 1, JANUARY 1972
