1020
Biomacromolecules 2009, 10, 1020
2009, Volume 10 Eun Seok Gil, Jianshu Li, Huining Xiao, and Tao Lu Lowe*: Quaternary Ammonium β-Cyclodextrin Nanoparticles for Enhancing Doxorubicin Permeability across the In Vitro Blood-Brain Barrier Page 506. Section 1, Introduction: The Reference 28 in the last paragraph is deleted. Page 506. Section 2.2, the synthesis protocol: correct to “Briefly, β-CD (5 mmol, 5.675 g) was dissolved in NaOH aqueous solution (20 mL, 0.9 M) with stirring at 25 °C for 24 h. Choline chloride [2.5 mmol (0.349 g), 10 mmol (1.396 g), 20 mmol (2.792 g), or 30 mmol (4.189 g)] was subsequently fed into the solution and epichlorohydrin [75 mmol (6.939 g)] was added at a flow rate of about 0.1 mL · min-1.” The concentration of hydrochloride acid solution: correct to 3 M. The denotation for each QAβCD: correct to “Each QAβCD is denoted as 1-WN, where W and N denote the feeding molar ratios of epichlorohydrin to β-CD and choline chloride to β-CD, respectively.” Reference 28, correct to ref 40. Page 506. Section 2.3.1, the preparation of QAβCD nanoparticle 1-15-2/DOX complexes: correct to “The QAβCD nanoparticle 1-15-2/DOX complexes were prepared by mixing QAβCD 1-15-2 (5 mg · mL-1, 3.9 mM of βCD unit) and DOX (2.1 mg · mL-1, 3.9 mM) in D2O at 1:1 molar ratio of DOX to βCD unit, and storing the mixture at 4 °C for overnight.” Page 514. Section 4, Discussion: The ref 28 in the second column, last paragraph: correct to ref 40. BM900279C 10.1021/bm900279c Published on Web 03/17/2009
