books and software
Excellence in chromatography continues Advances in Chromatography, Volume 44 Edited by Eli Grushka and Nelu Grinberg Taylor & Francis, 2006, 350 pp, $190, www.taylorand francis.com
I
have read many volumes in Advances in Chromatography, especially when my friend and colleague Phyllis Brown was one of the coeditors. After she retired, another friend and colleague, Nelu Grinberg, became a coeditor, along with Eli Grushka. They carry on the same tradition of excellence.
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This volume has eight chapters, all written by well-recognized experts in their respective areas in chromatography and electroseparations. In many cases, those individuals responsible for the original, fundamental work are now the coauthors of the chapters in this book. The chapters all are well written, well referenced, and have the high-quality artwork and attention to detail common to all previous volumes. I was especially impressed by the authors’ knowledge of the fundamentals—not just the applications and examples, but the fundamentals, theory, and equations. It is all there—they do know their stuff. The chapters cover separations in multiple-channel microchips; temperature effects and lipophilicity measurements in LC; concepts and practice of multidimensional HPLC; HPLC in the pharmaceutical industry; polysaccharide phases for separating enantiomers;
A N A LY T I C A L C H E M I S T R Y / J A N U A R Y 1 , 2 0 0 7
chaotropic effects in reversed-phase LC; and chromatography of difficult and water-insoluble proteins with organic solvents (Alpert). What a list of topics! I enjoyed reading almost every chapter, but perhaps I did not really pay enough attention to the others (could it have been late at night?). I have already used the chapter by Alpert in a fall 2006 graduate course in a discussion of applications of hydrophobic interaction LC (HILIC) for protein and peptide separations. This chapter is very relevant and applicable to HILIC of peptides and proteins and to smaller molecules as well. Volume 44 is a continuation of the excellent editing and writing we have come to expect in this prestigious series. I can recommend this volume to anyone interested in learning more about the topics indicated. Reviewed by Ira Krull, Northeastern University.
© 2007 AMERICAN CHEMICAL SOCIETY
