one to teach the intricacies of data collection and analysis without, a t the same time, challenging the student with the proper use and handling of radioisotopes. The theory for various aspects of scintillation spectrometry must he provided via another mode. The program entitled SIMULSCINT was written for a Commodore P E T microcomouter with 16 K RAM. It is availahle m a c3ssette rape f0;$40 frmn the Markrung Divison. Instructional Media Center, Michigan Srnte I'niversitv. .. ~ a sLansing, t MI 48824.
Simulation of Chemical and Enzyme Kinetics Experiments Clarence H. Suener and Don Hill Department of Biochemistry Michigan State University East Lansing, MI 48824 Computer programs for a microcomputer have been written to simulate a variety of laboratory techniques and methodologies. They are intended to be used to familiarize a student with the orohlems and orocesses involved in the anolication of a partiklar techniqie in the laboratory. They &e not intended to replace an actual laboratory experiment. Completion of the simulation provides the student with simulated data that can be analvzed hv accepted procedures. The aim is to reduce the time iequirid f o r a student to design, complete, and understand an experiment. I'rogrnm KINZYMI.:. The successful assay of nn enzvme and the determination of its kinetic parameters, the hlirhac.lis constant (K,,) and the maximum vebcity (\',:,,I, arr l~nsir rxperiences of all stl~dentsin hiorhemistry. In fact, it is reasonahle toargue that all profussional biuchrnlisu, no matter what t heir specific arm of interest, will hnve a need to wdrk with enzvmes a t some time in their careers. One of the iratures oienzymc ratalgsii that students uften have difficultv" in -erasoine is the extraordinnrv eifirimcv of the catalytic process. ' s t d e n t s will often conclude afte; an enzvme exoeriment that thev have an inactive enzvme menaration, when, in fact, the reaction was complete &fore they made their first observation. Another auestion often asked is ..what subsrratr
