Size and Structure of Bile Salt Micelles - Advances in Chemistry (ACS

Jul 22, 2009 - The aggregation numbers (Ag#) of free and conjugated di- and trihydroxy bile salts were studied by equilibrium ultracentrifugation and ...
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4 Size and Structure of Bile Salt Micelles Influence of Structure, Concentration, Counterion Downloaded by NORTH CAROLINA STATE UNIV on December 9, 2012 | http://pubs.acs.org Publication Date: June 1, 1968 | doi: 10.1021/ba-1968-0084.ch004

Concentration, p H , and Temperature DONALD M . SMALL Department of Medicine, Boston University School of Medicine, Boston, Mass. 02118

The aggregation numbers (Ag#) of free and conjugated di- and trihydroxy bile salts were studied by equilibrium ultracentrifugation and light scattering. The effect of concentration, counterion concentration, pH, temperature, and urea are shown. All trihydroxy bile salts form very small micelles (Ag#