LH-RH and Related Peptides (14) F. E. Norrington, R. M. Hyde, S. G. Williams, and R. Wootton, preceding paper in this issue. (15) J. G. Topliss and R. J. Costello, J . Med. Chem., 15, 1066 (1972). (16) R. M. Hyde, F. E. Norrington, S. G. Williams, and R. Wootton, manuscript in preparation.
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(17) Y. C. Martin and W. J. Dunn, J . Med. Chem., 16,578 (1973). (18) The computer selections given in this paper were all made using interactive computer programs written in the Focal language (PS/8 Focal) on a PDP8-e computer with 12k of core store and DECtape backup store. Copies of these programs are available on request from the authors.
Synthesis and Biological Activity of Luteinizing Hormone-Releasing Hormone and Related Peptides Derek J. Schafer,* Alan D. Black, John D. Bower, Reckitt & Colman Pharmaceutical Division, Hull, United Kingdom
and D. Barry Crighton University of Nottingham School of Agriculture, Sutton Bonington, United Kingdom. Received November 18,1974 Syntheses of the decapeptide luteinizing hormone-releasing hormone,
