Synthesis of 5-azacytidine-6-13C and-6-14C

(10) R. A. Scherrer, C. V. Winder, and F'. W. Short, Ahstracts of the 9th National Medicinal Chemistry Symposium ~f the. American Chemical Society. Mi...
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598 Journal of Medicinal Chemistry, 1977, Vol. 20, No.4

(6) M. S. Newman, J. Am. Chenz. Soc., 60, 2947 (1938). (7) C. V. Winder, cJ. Wax, V. Burr, M. Been, and C. E. Rosiere, .4rch. l n t . Pharmucodyra. Ther., 116. 261 (1958). (8) G. Wilhelmi, Schweiz. M e d . Wochenschr., 79, S77 (1949). (9) D. *J. Finney, R. Latscha, R. M.Bennett, and P. Hsu, Tables for Testing Significance in a 2 X 2 Contingency Table", Cambridge University Press, New York, N.Y., 1963. (10) R. A. Scherrer, C. V. Winder, and F'. W.Short, Ahstracts of the 9th National Medicinal Chemistry Symposium ~f the American Chemical Society. Minneapolis, Minn., June 1964, p l l a -i. (11) T. 1 '. Shen, I n t . S y m p . Non-Steroidul Antiinf/ammcitorj, l h g s , Proc., 1964, 13 (1965).

Notes

(12) S. Wong, Annu. R e p . M e d . Chem., 10, 172 (1975), and previous papers in this series. (13) R. A. Scherrer in "Antiinflammatory Agents", Vol. I, R. A. Scherrer and M. W. Whitehouse, Ed., Academic Press, New York, N.Y., 1974, pp 34-39. (14) J. T. Craig, M. A. Pitt, K. W. Tan, and A. D. Woolhouse, Aust. J . Chem., 25, 837 (1972). (15) J. S. Kaltenbronn and T. 0. Rhee, J . M e d . Chem., 17,654 (1974). (16) F. S. Spring, J . C h e m . SOC.,1332 (1934). (17) D. H. Hey and R. Wilkinson, J . C h e m . Soc., 1030 (1940). (18) M. S. Newman and J. Blum, J. Am. C h e m . SCJC., 8 6 , 503 (1 964).

Synthesis of 5-Azacytidine-&I3Cand -614C Kenneth K. Chan,' James A. Staroscik, Schools o/ Pharmuc:,, a n d hl