in the assault on the protein molecule·..
ADVANCE
new automated
technic
... their
provides
rapid
size, occurrence
preparative
and quantitative
and distribution...and
The Technicon AutoAnalyzer system you see above may well make history in protein research. By an ingenious extension of multiple-analysis chromatography, it not only separates peptides for preparative purposes, but at the same time gives quantitative information. The column effluent is split into many streams. One stream is subjected to a system of continuous hydrolysis. Another stream, unhydrolyzed, is used as control. Both are reacted with Ninhydrin. Com parison of these gives information about the size of the peptide. Other parallel streams can be used simultaneously for specific amino acid reactions.
information
assures
on
peptides
detection.
Thus, the basic AutoAnalyzer® train can be aug mented and s h a p e d at will to p r o v i d e m o r e a n d more analytic information. In doing this, the system takes up where paper chromatography, electrophoresis and UV monitor ing leave off. These methods are generally adequate enough for limited qualitative findings only. The Technicon® peptide system is automated from beginning to end with thoroughgoing AutoAnalyzer efficiency, rapidity, and reliability. This versatile AutoAnalyzer reduces to hours the days now con scripted to the tedious task of peptide analysis.
T AFTER BEFORE
Section of a chromatogram shotving tryptic hydrolyzate of performic acid oxidized bovine pancreatic Ribonuclease before and after alkaline hydrolysis.
Ε C Η Ν I C Ο Ν C H R O M A T O G R A P H Y C O R P . Research Park · C h a u n c e y , Ν . Y.
Technicon International of C a n a d a , Ltd., M o n t r e a l ; Technicon Instruments C o m p a n y , Ltd., London,· Compagnie Technicon, Paris; Technicon G m b H , F r a n k f u r t / M . ; Technicon AB, Stockholm; Technicon, Bas!e ; Technicon Italiana S.r.L., Rome,- Technicon Equipment Pty., Ltd., Sydney,- Compagnie Beige Technicon, Brussels, C o n i t t c h A / S , Copenhagen