Downloaded by 198.91.36.79 on March 1, 2015 | http://pubs.acs.org Publication Date: June 1, 1977 | doi: 10.1021/bk-1977-0061.pr001
PREFACE Hphe application of digital computers to the design and study of organic syntheses has stimulated the interest of chemists and computer scientists alike. The field not only promises practical benefits in synthesis planning and chemical education but also contributes to many areas of theoretical interest such as synthetic strategies, reaction indexing, structure representation, substructural perception, computer graphics, molecular modelling, and artificial intelligence. Many concepts and techniques now being used in structure elucidation, structure-activity, and other chemical information systems werefirstdeveloped in the computer synthesis planning field. Since 1969 when thefirstpaper in this area appeared, several groups have pursued approaches to computer synthesis planning. The symposium from which this volume derives was the first meeting of all the major research groups in this field. The papers in this volume describe the state of the art of computer synthesis as viewed by the major research groups working in the area. The editors acknowledge the Petroleum Research Fund for partial support of the symposium through a travel grant to Ivar Ugi and thank Cynthia O'Donohue for her help as program chairman. W. TODD WIPKE W. JEFFREY HOWE
Santa Cruz, August 1977
CA
Kalamazoo, MI
vii In Computer-Assisted Organic Synthesis; Wipke, W., et al.; ACS Symposium Series; American Chemical Society: Washington, DC, 1977.
