The productivity of split-and-pool.The quality of parallel synthesis

Nov 12, 2010 - Advertisements that appeared within the print issues of Chem. Eng. News have been included in the C&EN Archives to provide a ...
0 downloads 0 Views 354KB Size
The productivity of split-and-pool.The quality of parallel synthesis.

*wr TDU CAN NOW rapidly and pooling batches of microchip Y economically synthesize encoded microreactors that are JL multi-milligram quantities physically separated from one of hundreds to thousands of another, combinatorial libraries of discrete compounds. No, we discrete compounds can be rapidly haven't changed the laws of synthesized. In this directed sortphysics, just creatively MicroKan® and MicroTube® reactorsing process, compounds are "split" applied them. by electronically reading their unique ID tag - not a random statistical process. The AccuTag®-l00 Combinatorial Chemistry The result is the rapid synthesis of exactly one disSystem uniquely combines the advantages of both crete copy of every unique compound in the library. parallel synthesis and split-and-pool. Parallel synthesis provides multi-milligram We Have Worked Out All the Details. quantities of discrete compounds. However, it is At IRORI, we have developed a robust combination difficult to rapidly synthesize thousands of glass encapsulated microchip tags, polymer microof compounds by parallel synthesis, reactors, sorting stations, and software to provide a comeven with automation. The tradiplete turn-key solution for combinatorial chemistry. tional split-and-pool technique To Learn More, Ask for the Details. addresses this limitation, but with severe consequences This technology is already being used in dozens - mixtures, or complex of pharmaceutical laboratories synthesizing thoumolecular encoding sands of compounds every month. To see how easy schemes. Now, the AccuTag it is to use the AccuTag System to System solves this dilemma. synthesize multi-milligram quantities of discrete compounds with ^ the productivity of split-andUnique Combinatorial Process. The AceuTag System uses an innovative process to implement a powerful form of split-andpool called "directed sorting." By splitting and

pool, call us at 619-546-1300 and well send you the details. E-mail: [email protected] / fax 619-546-3083

Contact us for the locations of our international CIRCLE 2 5 ON READER SERVICE CARD

distributors.

^\v I

R

O

R

I