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Using the SBRC assay to predict lead relative bioavailability in urban soils: contaminant source and correlation model Hong-bo Li, Di Zhao, Jie Li, Shiwei Li, Ning Wang, Albert L. Juhasz, Yong-Guan Zhu, and Lena Q. Ma Environ. Sci. Technol., Just Accepted Manuscript • DOI: 10.1021/acs.est.6b00480 • Publication Date (Web): 19 Apr 2016 Downloaded from http://pubs.acs.org on April 20, 2016
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Using the SBRC assay to predict lead relative bioavailability in urban soils:
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contaminant source and correlation model
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Hong-Bo Li,† Di Zhao,† Jie Li,† Shi-Wei Li,† Ning Wang,‡ Albert L. Juhasz,ǁ Yong-Guan Zhu,§
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and Lena Q. Ma,*,†,┴
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State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment,
Nanjing University, Nanjing 210046, People’s Republic of China ‡
Institute of Agricultural Resources and Environments, Jiangsu Academy of Agricultural
Sciences, Nanjing 210014, People’s Republic of China ǁ
Future Industries Institute, University of South Australia, Mawson Lakes, SA 5095, Australia
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Key Laboratory of Urban Environment and Health, Institute of Urban Environment, Chinese
Academy of Sciences, Xiamen 361021, People’s Republic of China ┴
Soil and Water Science Department, University of Florida, Gainesville, Florida 32611,
United States
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*Corresponding author: State Key Laboratory of Pollution Control and Resource Reuse,
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School of the Environment, Nanjing University, Nanjing 210046, People’s Republic of China,
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Tel./fax: +86 025 8969 0631, E-mail:
[email protected] 1
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TABLE OF CONTENT
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ABSTRACT: Using in vitro bioaccessibility assays to predict Pb relative bioavailability
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(RBA) in contaminated soils has been demonstrated, however, limited research was
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performed on urban soils having lower Pb levels. In this study, 162 soils from urban parks in
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27 capital cities in China were measured for Pb bioaccessibility using the SBRC assay, with
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Pb-RBA in 38 subsamples being measured using a mouse-kidney assay. Total Pb
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concentrations in soils were 9.3–1198 mg kg–1, with 92% of the soils having Pb
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concentrations 100 mg kg–1. Based on a stable isotope
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fingerprinting technique, coal combustion ash was identified as the major Pb source,
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contributing to the increased Pb bioaccessibility with increasing Pb concentration. Lead-RBA
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in soils was 17−87%, showing a strong linear correlation with Pb bioaccessibility (r2=0.61),
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with cross validation of the correlation based on random sub-sampling and leave-one-out
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approaches yielding low prediction errors. Based on the large sample size of 38 soils, this
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study demonstrated that the Pb-RBA predictive capability of the SBRC assay can be extended
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from mining/smelting impacted soils to urban soils with lower Pb levels.
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INTRODUCTION
Lead (Pb) exposure from the environment is a serious hazard for children, with elevated
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Pb exposure causing adverse effects on their neurodevelopment.1 Mounting evidence has
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shown occurrence of Pb-associated neurodevelopmental deficits at low blood Pb levels
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(BLLs) (e.g.,
