Virtual Issue on Crystallisation and Polymorphism ... - ACS Publications

Sep 20, 2013 - The subject of crystallisation and polymorphism has been a hot topic for the last couple of decades. As a result,. Organic Process Rese...
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Virtual Issue on Crystallisation and Polymorphism in Organic Process Development: 25 Papers Specially Selected by the Editor

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he subject of crystallisation and polymorphism has been a hot topic for the last couple of decades. As a result, Organic Process Research and Development (OPR&D) has published a number of special feature sections on the subject in 2000, 2003, 2005, 2009, and recently in the March 2013 issue.1 No doubt, given the importance of the subject to the pharmaceutical, electronics, and other industries, the special feature sections on this subject will appear again in 2015 or 2016 since it remains a hot topic. There are still many excellent papers on the subject, however, which do not appear within these special feature sections and are published as full papers in the regular issues. This virtual issue aims to select the best papers from OPR&D over the last 3 to 4 years, whether they appeared in special feature sections or not. Whilst it is possible for the reader to easily select from the OPR&D Web site all papers that have appeared on the subject in a given period, that search may pull up hundreds of papers. My selection hopefully guides you to what I think are the 25 most important papers in recent history. This was a difficult choice from the large number of excellent papers published in the journal since 2010 on the topic of crystallisation and polymorphism. There are also quite a few papers from earlier periods which are also very important for industry and could make a claim for inclusion (for example the paper by Wolfgang Beckmann on seeding strategies2) but fell outside our initial guidelines of recent publication. My apologies to those authors who were left out for this reason. I do hope readers enjoy reading (or hopefully rereading) this limited selection which very much reflects my own personal interests in this fascinating topic. I would appreciate feedback from readers on this virtual issue; other ACS journals’ virtual issues have proved popular, and I expect OPR&D’s to be the same. If that is the case, we will offer more virtual issues, and suggestions from readers for future topics are most welcome. Happy reading!



Trevor Laird, Editor-in-Chief AUTHOR INFORMATION

Notes

Views expressed in this editorial are those of the author and not necessarily the views of the ACS.



REFERENCES

(1) Org. Process Res. Dev. 2013, 17(3), 443−602 (2) Beckmann, W. Org Process Res Dev 2000, 4, 372−383.

Published: September 20, 2013 © 2013 American Chemical Society

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dx.doi.org/10.1021/op400220h | Org. Process Res. Dev. 2013, 17, 1219−1219