Aggregation Aggravation? Absolute Macromolecular Characterization is the answer!
W
ant to detect biopolymer aggregation simply and quickly? Want to study aggregation and distinguish among dimers, trimers and higher aggregation states? Read on! Just by coupling our DAWN" Model F multiangle laser light scattering detector to your existing chromatography line, you'll be able to see aggregation phenomena that NMR and UV detectors miss routinely, since our sensitivity is directly proportional to the mass detected. In addition, you can determine absolute molecular weights, sizes, distributions and confor mations of your samples without resorting to inappropriate experimental assumptions like column calibrations with unrelated "standards", so-called "universal constants" or other "fudge-factors". You can perform rapid studies of aggregation in our advanced light scattering instruments that have no lenses, mirrors, or prisms that could become misaligned, damaged or dirty. You could, for example, work off-line, in a batch mode, or on-line using our new ASTRA chromatography software that's so powerful and easyto-use that some people think a giant software company wrote it! In the time that it takes an old-fash-
ioned light scattering instrument to make one measurement, we can make tens-of-thousands. We can work with concentrations your NMR can't, and see aggregation your UV won't! In short, we enable you to do experiments that were once considered impossible to perform. With our Wyatt/ Optilab 903 Interferometric Refractometer you can determine the specific refractive index increment, dn/dc, of a sample in minutes, and do it with a sample 2,000 times smaller than some other instruments require. And when you're not making off-line measurements, the 903 becomes an RI detector of unmatched simplicity. Our standard red Helium-Neon laser system covers a range of molecular weights from a few thousand daltons to hundreds of millions. But you can get below a thousand daltons—with great signal-to-noise— using our blue Argon-ion laser system. Jump light years ahead of the competition and end your aggregation aggravation! Call us at (805) 963-5904 for a complete information package of brochures, price list, and application notes. We can't guarantee that you won't have aggregation, but the chances are that you'll finally be able to see it!
Call today for more information and your FREE full-color brochure: (805) 963-5904 31991 Wyatt Technology Corporation
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Wyatt Technology CORPORATION 802 E. Cota St.· Santa Barbara, CA 93103 Tel: (805) 963-5904 · Fax: (805) 965-4898
