Drug Metabolism Concepts - American Chemical Society

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Drug Metabolism Concepts

Jerina; Drug Metabolism Concepts ACS Symposium Series; American Chemical Society: Washington, DC, 1977.

Jerina; Drug Metabolism Concepts ACS Symposium Series; American Chemical Society: Washington, DC, 1977.

Drug Metabolism Concepts Donald M . Jerina, EDITOR The National Institutes of Health

A symposium co-sponsored by the Division of Medicinal Chemistry and the Division of Analytical Chemistry at the 172nd Meeting of the American Chemical Society, San Francisco, Calif., August 31,

ACS

1976

SYMPOSIUM

SERIES

AMERICAN CHEMICAL SOCIETY WASHINGTON, D. C. 1977

Jerina; Drug Metabolism Concepts ACS Symposium Series; American Chemical Society: Washington, DC, 1977.

44

Library of Congress CIP Data Drug metabolism concepts. (ACS symposium series; 44 ISSN 0097-6156) Includes bibliographical references and index. 1. Drug metabolism—Congresses. 2. Cytochrome P-450 —Congresses. 3. Benzpyrene—Metabolism—Congresses. 4. Carcinogenesis—Congresses. I. Jerina, Donald M., 1940- . II. American Chemical Society. Division of Analytical Chemistry. III. American Chemical Society. Division of Medicinal Chemistry. IV. Series: American Chemical Society. Symposium series; 44. RM301.D76 ISBN 0-8412-0370-9

615'.7 ACSMC8

77-2279 44 1-196

Copyright © 1977 American Chemical Society All Rights Reserved. No part of this book may be reproduced or transmitted in any form or by any means—graphic, electronic, including photocopying, recording, taping, or information storage and retrieval systems—without written permission from the American Chemical Society. PRINTED IN THE UNITED STATES OF AMERICA

Jerina; Drug Metabolism Concepts ACS Symposium Series; American Chemical Society: Washington, DC, 1977.

ACS Symposium Series Robert F. Gould, Editor

Advisory Board Donald G. Crosby Jeremiah P. Freeman E. Desmond Goddard Robert A. Hofstader John L. Margrave Nina I. McClelland John B. Pfeiffer Joseph V. Rodricks Alan C. Sartorelli Raymond B. Seymour Roy L. Whistler Aaron Wold

Jerina; Drug Metabolism Concepts ACS Symposium Series; American Chemical Society: Washington, DC, 1977.

FOREWORD The ACS SYMPOSIUM S E R I E S was founded in 1974 to provide a medium for publishing symposia quickly in book form. The format of the S E R I E S parallels that of the continuing ADVANCES IN CHEMISTRY S E R I E S except that in order to save time the papers are not typeset but are reproduced as they are submitted by the authors in camera-ready form. As a further means of saving time, the papers are not edited or reviewed except by the symposium chairman, who becomes editor of the book. Papers published in the ACS SYMPOSIUM S E R I E S are original contributions not published elsewhere in whole or major part and include reports of research as well as reviews since symposia may embrace both types of presentation.

Jerina; Drug Metabolism Concepts ACS Symposium Series; American Chemical Society: Washington, DC, 1977.