Eisustiruaii. -Briefs FOR MAY
•111 BIS Recently, we "Briefed" two new research chemicals with 4-carbon ring structures... a methyl-substituted cyclobutanedione and the corresponding diol. Much to our chagrin, we promptly ran through the modest supply of these compounds which our research people had prepared with loving care for our sampling purposes. At which point they threw in the towel and went back to their mortar and pestles to add to their basic knowledge of this class of compounds. So here we go again. But this time we're ready. A pilot plant which we defy you to oversubscribe is merrily bubbling away. And from our research laboratories, a steady stream of reaction information is being added to our published literature on the subject. The selected reactions below will give you some idea of the direction of our work. For the rest, send in the coupon. p . S . Incidentally, the derivatives mentioned are not available. Our literature, though, provides complete procedures for preparation. DG0BOEB
2,2,4,4-Tetramethyl1,3-cyclobutanediol Esterification
Condensation c c
CWC OH
Ç
,0-Si+
CISi(CH 3 ) 2 CI
Η GC
Cyanoethylation and Hydrolysis B14
Qc
Tetramethyl-1,3-cyclobutanedione
Η
Keto ester formation
>=o
ROH OH-
c o c o ->*
I II I II C-C-C-C-OR I I
c
c
Keto amide formation cvc >=o
RNH2
cc
c o c o
I II I II I ->-C-C-C-C-NI I C C
Eastman Chemical Products, Inc. Kingsport, Tennessee
Condensation
X
c c
x
H2NOH
Chemicals Division Eastman Chemical Products, Inc. subsidiary of Eastman Kodak Company Kingsport, Tennessee
- > • H O N = / N = NOH C C H2
Please send new data sheets on B 1 4
EN
B I S
C C H2N Η
Η NH 2
Name
C C Title
Eastman C h e m i c a l Products, Inc. Kingsport, Tennessee
Company
Address
CUP A N D FILE
Zone No.
State
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