Efficient Convergent Synthesis of 1,25-Dihydroxyvitamin D3

ORGANIC LETTERS 2003 Vol. 5, No. 17 3167

Additions and Corrections

Vol. 5, 2003

Scheme 3

Takeshi Hanazawa, Akiko Koyama, Takeshi Wada, Eiko Morishige, Sentaro Okamoto, and Fumie Sato* Efficient Convergent Synthesis of 1R,25-Dihydroxyvitamin D3 and Its Analogues by Suzuki-Miyaura Coupling. Page 524. Scheme 3 contains incorrect reaction conditions and yields; the correct Scheme 3 is shown here. The following corrections are also needed in the text in the paragraph regarding Scheme 3 on page 524, column 2. In line 10, the yield for compound 10 should be 51%, not 88%. In line 17, the solvent for the reaction with DBU should be toluene, not CH2Cl2. In line 18, the overall yield of 1 should be 45%, not 76%. Supporting Information. The data initially shown in Supporting Information were those related to the 1-epi-[1,25(OH)2-VD3] and not [1,25-(OH)2-VD3]. The Supporting Information has been corrected. These mistakes occurred when we simultaneously prepared [1,25-(OH)2-VD3] and three other possible A-ring diastere-

omers of 1,25-(OH)2-VD3. The full paper containing these results is now in preparation. OL035278L 10.1021/ol035278l Published on Web 07/29/2003