Electrospinning Bioactive Supramolecular Polymers from Water

Apr 4, 2014 - The solution was passed through a 0.22 μM filter and injected into a preparative-scale reverse-phase HPLC running a mobile phase gradie...
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Article pubs.acs.org/Biomac

Open Access on 04/04/2015

Electrospinning Bioactive Supramolecular Polymers from Water Alok S. Tayi,† E. Thomas Pashuck,† Christina J. Newcomb,† Mark T. McClendon,‡ and Samuel I. Stupp*,†,§,∥,⊥ Departments of †Materials Science and Engineering, ‡Chemical and Biological Engineering, and §Chemistry, Northwestern University, Evanston, Illinois 60208 United States ∥ Feinberg School of Medicine and ⊥Institute for BioNanotechnology in Medicine (IBNAM), Northwestern University, Evanston, Illinois, 60211 United States S Supporting Information *

ABSTRACT: Electrospinning is a high-throughput, low-cost technique for manufacturing long fibers from solution. Conventionally, this technique is used with covalent polymers with large molecular weights. We report here the electrospinning of functional peptide-based supramolecular polymers from water at very low concentrations (