Engineered Cell Penetrating Peptides - ACS Symposium Series (ACS

Nov 15, 2017 - This book chapter aims to give a general overview on the various classes of CPPs, the cell-entry mechanisms, and published pre-clinical...
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Chapter 13

Engineered Cell Penetrating Peptides

Downloaded by UNIV OF FLORIDA on November 21, 2017 | http://pubs.acs.org Publication Date (Web): November 15, 2017 | doi: 10.1021/bk-2017-1271.ch013

Weili Ma and Won H. Suh* Department of Bioengineering, College of Engineering, Temple University, 1947 N. 12th St., Philadelphia, Pennsylvania 19122, United States *E-mail: [email protected].

Cell penetrating peptides (CPPs) have shown promise in delivery of therapeutics into cells. CPPs can be described as short amino acid sequences, typically