Engineering an Arginine Catabolizing ... - ACS Publications

Zhang, Clifford Longley, Mary Mehlig, Virna Borowski,. Prakash Sai, Manickam Viswanathan, Eun Jang, Gerald. Petti, Sam Liu, Karen Yang, and David Filp...
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Bioconjugate Chem. 2007, 18, 605

605

CORRECTIONS Volume 17, Number 6, November/December 2006.

Maoliang Wang, Amartya Basu, Thomas Palm, Jack Hua, Stephen Youngster, Lisa Hwang, Hsien-Ching Liu, Xiguang Li, Ping Peng, Yue Zhang, Hong Zhao, Zhihua Zhang, Clifford Longley, Mary Mehlig, Virna Borowski, Prakash Sai, Manickam Viswanathan, Eun Jang, Gerald Petti, Sam Liu, Karen Yang, and David Filpula* ENGINEERING AN ARGININE CATABOLIZING BIOCONJUGATE: BIOCHEMICAL AND PHARMACOLOGICAL CHARACTERIZATION OF PEGYLATED DERIVATIVES OF ARGININE DEIMINASE FROM MYCOPLASMA ARTHRITIDIS The original publication (1) contained an error in Figure 3. The correct figure is below.

Figure 3. pH dependence of M. arthritidis ADI and PEG-ADI activity. (A) ADI, 12 kDa PEG-ADI, and 20 kDa PEG-ADI activity are measured at eight pH values. Values (%) are shown relative to native ADI at pH ) 6.5 (100%). (B) pH profile of specific activity of P. putida ADI. (C) Stability studies in rat plasma for M. arthritidis ADI, 12 kDa PEG-ADI, and 20 kDa PEG-ADI stored at 4, 25, and 37 °C, and assayed at 10 min, 18 h, or 5 days. Relative activity is shown with 100% corresponding to the 4 °C stock solution. BC060380Z 10.1021/bc060380z Published on Web 03/03/2007