Engineering Stability-Tunable DNA Micelles Using Photocontrollable

Dec 12, 2017 - Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemi...
0 downloads 6 Views 5MB Size
www.acsnano.org

Engineering Stability-Tunable DNA Micelles Using Photocontrollable Dissociation of an Intermolecular G‑Quadruplex Cheng Jin,† Xiaojing Liu,† Huarong Bai,† Ruowen Wang,†,§ Jie Tan,† Xuehui Peng,‡,⊥ and Weihong Tan*,†,‡,§ †

Molecular Science and Biomedicine Laboratory, State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, College of Life Sciences, Aptamer Engineering Center of Hunan Province, Hunan University, Changsha, Hunan, 410082, China § Institute of Molecular Medicine, Renji Hospital, Shanghai Jiao Tong University School of Medicine, and College of Chemistry and Chemical Engineering, Shanghai Jiao Tong University, Shanghai, China ⊥ Key Laboratory of Interfacial Reaction & Sensing Analysis in Universities of Shandong, School of Chemistry and Chemical Engineering, University of Jinan, Jinan, Shandong 250022, People’s Republic of China ‡ Department of Chemistry and Department of Physiology and Functional Genomics, Center for Research at the Bio/Nano Interface, UF Health Cancer Center, UF Genetics Institute, McKnight Brain Institute, University of Florida, Gainesville, Florida 32611-7200, United States S Supporting Information *

ABSTRACT: Because of their facile preparation, small size (