comprehensive reviews of the major discoveries and theories recorded during a period of 25-30 years or more; a few cover only the past 8-10 years. Eaoh presentation includes a critical evaluation of the experimental results reported, and contains details of specific definitions, techniques far isolation, identification, and determination of structures of various proteins, An extensive bibliography is included a t the end of each chapter. Both volumes include adequate author and eubjeet indexes. Volume 11 also carries cumulative author and subject indexes for Volumes 6 t o 10,inclusive. The topios covered in Volume 10 am: The Nature of Phosphorus Linkages in Phosphoproteina, Gertrude A. Perlmann, (evidence for diestur and pyrophosphate bonds as cros~.linkagesbetween peptide chains); Metabolism of the Aromatic Amino Acids, C. E. Dagliesb, (details of metabolism of phenylalanine, tyrosine and try,?to,han); Hydrogen Ion Equilibria in Native and Denatured Proteins, J. Steinhardt and E. RI. Zaimr, (newer interpretations of titration curves of proteins); Fish Proteins, G. Hamoir, (physicochemical properties of proteins of the muscles, enzymes, blood, and spematoaoa of fish); The Sea. as s. Potential Source of Protein Food, L. A. Walford and C. G. Wilber, (critical analysis of the availability, economio and esthetic suitability and biologicel value of marine organisms for human food); Zinc and Metalloenaymes, B. L. Vallee, (coordination chemistry of zinc, especially in various enzyme 8y~tems). Topics included in Volume I 1 are: Protein Structure in Relation t o Function and Biosynthesis, C. B. Anfinsen and R. R . Redfield, (correlation of amino acid sequences, of covalent and non-covalent structures and of cross-linkages with functions of several proteins); Hormones of the Anterior Pituitary Gland. Part I. Growth and Adrenoeartieotropic Hormones, C. H. Li, (evidence for proposed structures); Column Chromatography of Peptides and Proteins, S. Moore and W. H. Stein, (factors influencing the precise chromatographic separation of proteins and peptides); Countercurrent Distribution in Protein Chemistry, P. von T a d and R. Signer, (principles, technique, applications and factors influencing the use of countercurrent procedures in the separation of proteins and peptides); Complex Formation between Metallio Cations and Proteins, Peptides, and Amino Acids, F. R. N. Gurd and P. E. Wilcox, (types and meohanisms of form* tion of complexes between various cations and proteins, peptides and amino acids, physical and chemical properties of various specific complexes, effects of metal ions on properties of proteins); Measurement and Interpretation of Diffusion Coefficients of Proteins, I,. J. Gosting, (physical chemistry, methods of measurement and interpretation of results of diffusion coefficients ss applied to proteins, interacting flours in systems of three or more components).
VOLUME 34, NO. 12, DECEMBER, 1957
ESSENTIAL PRINCIPLES OF ORGANIC CHEMISTRY James Cason, Professor of Chemistry, Univ e ~ s i bof California, Berkeley, California. Prentioe-Hall, Inc., Englewwd Cliffs, New 530 pp. 16 X 23.5 Jersey, 1956. xi
+
"n.
INTHE preface of this text the author presents the conviction that the first course in elementary organic chemistry should deal with the principles of organic chemistry. This involves a selection of what src principles, what is to be included, and what is t o be omitted. It appears to the reviewer that the author has made a workable selection of all phases of elementary organio chemistry so that the student can become familiar, although not averwhelmed, with what is important. The author believes "that when a book is eanstructed as a. combination of reference book and textbook, much of its usefulness to the elementary student is last, for he is not sufficiently sophintiertted t o discriminate between the two typen of material. The oresent book is oresented as a textbook for use in an elementary course eonsisting of about eightv-five one-hour leeture periods." Hence, if the instructor is looking for a text which contains chapters on the aliphatic nitro compounds, the aliphatic sulfur compounds, alkaloids, terpenes and steroids, he will not find them in this text. Certainly such topics are mentioned but not in sections devoted exclusively t o a lengthy account of their chemidtry and propnties. Of the many heterocyclic compounds, only three ring ~ y s t e m sare studied. Pyridine, quinoline and isoqninoline are presented as a final aection in s. relative extensive manner since the study of these compounds malres possible a review and correlation of the aliphatic and aromatic chemistry previously dincussed. The text begins with the study of ethyl aleohnl, since this compound is representative and can be utilized t o illustrate a number of properties plus ideas of structure, rules of valence, functional groups and naming. The text then follows the general order of elementary texts except that the organization is around the systematic presentation of plinciples, not the systematic presentation of facts. Theore6 ical ideas always precede the corresponding descriptive material. The Nature of the Chemical Bond is considered in the second chapter and elaborated later as Nature of Multiple Bonds, Concerning Mechanism of Organic Reactions, and Resonance and Hydrogen Bonding. Although there is much evidence of good o r ~ a n i cchemical pedagogy, one particular section which the reviewer found interesting was the description in Chapter 8 of how 8. student should approach a multistep synthesie. Usually such teaching devices are left for the individual instructor, but some aid frcm the text is always valuable. Chapter 37 on The Literature of Organic Chemistry is another such aid t o the instructor. It eoitomizes the philosophy of the text that only the fundamental ideas can be presented in the introductory course, but that the student can be awakened t o the infinite horizon of
organio chemistry t o be found in the original research literature. reactions and stereoisomerism are well done. The book is well bound. The field of organic chemistry has become so complex that no elementary course can hope t o cover a view of all the new factual material. The present text has been written from the point of view that beginning students of organic chemistry must be introduced t o the principles of the field in such a manner that they may grow in an understanding of theory and immensity of the field. The reviewer recommends this text as one which will serve the needs of sll introductory organic chemistry olasses. D. J. COOK
D e P ~ u wU ~ ~ v ~ n s t r r G n e e n c ~ s ~INDIANA ~e.
TECHNIQUE OF ORGANIC CHEMISTRY. VOLUME 3,PART I: SEPARATION AND PURIFICATION Edited by Arnold Weissberger, Research Laboratories, Eastman Kodak Co., Rochester, New York. Second revised and augmented edition. Interscience Publishers, Inc., New York, 1956. ix X 873 pp. 16 X 23.5 Em. $17.50. A o v m c ~ sin the methods and techniques of separation and purification of organio compounds are reflected in the difference in this revised edition and its 1950predecessor. The earlier edition contained in addition to chapters dealing with eonvmtionitl methoda of separation and purification, a. chapter on Cooling and Heating and one on Miiing. These two topios together with a number of other labomtory engineering techniques are the subject matter for Part I1 of the revised Volume 3. Again, distillation, adsorption, and chromatography me omitted from this volume since they are covered in Volumos 4 and 5 of the Techniques series. This volume has the f o l l o ~ n gsections dealing with diffusion methods which were not included in the 1950 edition: Thermal Diffusion of Organic Liquide, by A. L. Jones, Barrier Separation, by Karl Kammermeyer, and Zone Electrophoresis, by E. MacWilliam. These three topics together with the revised seotion on Dialysis and Electrodialysis, by R. Eliot Stauffer, constitute Chapter I of this aecond edition. Eaeh of these section6 appears t o be quite complete from the standpoint of theory, general discussion including apparatus, and applications. There are many helpful line drawings and diagrams as well as numerous tables and a few pictures of apparatus. The revised seotion by Stauffer deserves special comment for i t not only includes a new section on electrodecantation but also has tan extremely good general reference seotion of 136 items, many of which are annotated. Chapter 11, Laborstory Extraction and Counter-cutrent Distribution., bv" Lvmon " Craig and David Craig, has a new section by Edward G. Scheibel an LiquidLiquid Extraction for Incressed Quantity. ~
