i n my s h o e s
Exploring the proteomics universe Researchers co-opt astronomy software to look for differences between complex mixtures of proteins.
A
COURTESY OF NASA
A slide projector shined light through used fluorescent dyes that are based on lthough 2D gel electrophoresis is a hole cut in the top of the cabinet. A cyanine (Cy). “We sat down one day at popular, it isn’t known for its abilicooled CCD camera collected two imlunch and came up with the design for ty to detect proteins that are present at ages for each gel. The excitation filter in the dyes,” Minden says. It sounds a litlow concentrations. But, with the help front of the projector was changed betle too easy, but the researchers figured of software designed to analyze images tween images to select for first one dye out what they needed in about half an of galaxies, Jonathan Minden and coland then the other. leagues at Carnegie Mellon Initially, the researchers University (CMU) can discreated a two-frame movie cern gel spots that contain by rapidly alternating the
