Femtosecond dynamics reveal two paths in Diels-Alder reaction

Publication Date: October 07, 1996. Copyright © 1996 American Chemical Society. ACS Chem. Eng. News Archives. Cite this:Chem. Eng. News 1996, 74, 41,...
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science/technology William M. Baird, professor of medicinal chemistry and director of the Purdue Carcinogenic polycyclic Cancer Center at Purdue University, aromatic hydrocarbons West Lafayette, Ind., and his colleagues there have studied the metabolic activation of polycyclic aromatic hydrocarbons (PAHs), particularly the potent animal carcinogen dibenzo[a,/]pyrene (DB[a,/]P). Using radiolabeling techniques and high-pressure liquid chromatography, the researchers analyzed the reaction Dibenzo[a,/]pyrene products formed when DB[