Fibronectin Adsorption, Cell Adhesion, and Proliferation on

May 5, 2010 - hut surfaces coated with fibronectin compared to the uncoated flat tantalum ... fibronectin cell-binding domains observed on the hut str...
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Fibronectin Adsorption, Cell Adhesion, and Proliferation on Nanostructured Tantalum Surfaces A. Dolatshahi-Pirouz,†,‡ T. Jensen,†,§ David Christian Kraft,⬜ Morten Foss,†,* Peter Kingshott,† John Lundsgaard Hansen,‡ Arne Nylandsted Larsen,‡ Jacques Chevallier,‡ and Flemming Besenbacher†,‡ †

Interdisciplinary Nanoscience Center (iNANO), and ‡Department of Physics and Astronomy, Aarhus University, Aarhus, Denmark, §Orthopaedic Research Laboratory, Aarhus University Hospital, Aarhus, Denmark, and ⬜Department of Orthodontics, School of Dentistry, Aarhus University, Aarhus, Denmark

ABSTRACT The interaction between dental pulp derived mesenchymal stem cells (DP-MSCs) and three different tantalum nanotopographies with and without a fibronectin coating is examined: sputter-coated tantalum surfaces with low surface roughness