Flemistrictin-B: a Chalcone from the Seeds of Lonchocarpus sericeus

Nov 1, 1986 - Five New Prenylated Stilbenes from the Root Bark of Lonchocarpus chiricanus. Jean-Robert Ioset, Andrew Marston, Mahabir P. Gupta, and Ku...
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Nov-Dec 19861

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ACKNOWLEDGMENTS

The work was supported by the National Science Foundation (Grant BSR-8402017). We wish to thank Tina Ayen for the collection and identification of A . saltillensis. LITERATURE CITED 1. 2. 3. 4. 5. 6. 7. 8.

S. Yu, D.A. Gage, N. Fang, and T.J. Mabry, J . Nat. Prod., 49, 18 1 (1986). S. Yu, J. Nocris, N. Fang, and T.J. Mabry, J . Nat. Prod., 49, 553 (1986). S . Yu, N. Fang, and T.J. Mabry, Rev. Latinoam. Quim., (in press). N. Fang, S. Yu, and T.J. Mabry, Phytorhenzstry, 25, 2665 (1986). N. Fang and T.J. Mabry,J. N a t . Prod., 49, 737 (1986). L. Quijano, F. Malanco, and T. Rios, Tetrahedron, 26, 285 1 (1970). F. Bohlmann and M. Grenz, Chem. Ber., 110,132 1 (1977). T.J. Mabry, K.R. Markham,and M.B. Thomas, “The Systematic Identification of Flavonoids,” Springer-Verlag, New York, 1970.

R e a i d 24 July 1986

FLEMISTRICTIN-B: A CHALCONE FROM THE SEEDS OF LONCHOCARPUS SERICEUS EL-HADIN. MAHMOUD’and PETERG. WATERMAN*

Phytorhemistry Research Laboratories, Departmiat of Phannary (Phann. Chem.), University OfStrathrlyde, G l a s g m GI 1 XW, Srotland, U K Lonrhccarprrs sm’reus (Poir.) H.B. & K. (Leguminosae, Papilionoideae) is a small forest tree found in both West Africa and the neotropics (1). In a previous investigation of seeds of Ghanaian origin the chalcones lonchocarpin, derricin, derricidin (cordoin), isocordoin, and 4-hydroxylonchocarpin, and the flavanone isolonchocarpin were reported (2). An examination of the roots of material of South American origin yielded all of the above with the exception of the last two named chalcones (3). A re-examination of seeds from this species yielded four chalcones, three ofwhich were characterized as the previously recorded lonchocarpin, derricin, and isocordoin and the fourth as the dihydrofuranochalcone, flemistrictin-B, which had not previously been reported from Lonrhorarpus but only from another papilionaceous taxon, Flemingia strirta (4). The 13C-nmrspectrum of flemistrictin-B is reported for the first time. EXPERIMENTAL

PLANT m T E W . - L . sm.reus seeds were collected in Ghana. A voucher specimen has been lodged in the Caplogical Collection of the Herbarium of the Royal Botanic Gardens, Kew. EXTRACTIONAND IsoLATION.