Anal. Chem. 1998, 70, 1462-1467
Articles
Flow Injection Immunoanalysis Based on a Magnetoimmunosensor System Sı´lvia Sole´, Salvador Alegret, Francisco Ce´spedes, and Esteve Fa`bregas*
Grup de Sensors & Biosensors, Departament de Quı´mica, Universitat Auto` noma de Barcelona, 08193 Bellaterra, Catalonia, Spain Teo´filo Dı´ez-Caballero
Biosensores, S. L., Avd. Ausias March, s/n. 12593 Monco` far, Castello´ de la Plana, Spain
A new immunosensor integrated to a flow system has been developed. It is based on magnetic immunoparticles immobilized on a solid-state transducer using a magnetic field. The described technique renews the immunoparticles reproducibly for each analysis allowing a good measurement precision. The developed experimental approach permits the implementation of an automated immunoassay that is quick (analytical cycle
